Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Getting

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Don't Have

Insidious Dreams

As an additional cost to cast this spell, discard X cards.
Search your library for X cards, then shuffle and put those cards on top in any order.

Ebony Charm

Choose one —
• Target opponent loses 1 life and you gain 1 life.
• Exile up to three target cards from a single graveyard.
• Target creature gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Death Watch

Enchant creature
When enchanted creature dies, its controller loses life equal to its power and you gain life equal to its toughness.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Have

Mind Sludge

Target player discards a card for each Swamp you control.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Kaervek's Spite

As an additional cost to cast this spell, sacrifice all permanents you control and discard your hand.
Target player loses 5 life.

Monomania

Target player chooses a card in their hand and discards the rest.

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Noxious Vapors

Each player reveals their hand, chooses one card of each color from it, then discards all other nonland cards.

Lich's Mirror

If you would lose the game, instead shuffle your hand, your graveyard, and all permanents you own into your library, then draw seven cards and your life total becomes 20.

Mindstab

Target player discards three cards.
Suspend 4—{B} (Rather than cast this card from your hand, you may pay {B} and exile it with four time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Mind Shatter

Target player discards X cards at random.

Phthisis

Destroy target creature. Its controller loses life equal to its power plus its toughness.
Suspend 5—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with five time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Absorb Vis

Target player loses 4 life and you gain 4 life.
Basic landcycling {1}{B} ({1}{B}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Torment of Venom

Put three -1/-1 counters on target creature. Its controller loses 3 life unless they sacrifice another nonland permanent of their choice or discard a card.

Davriel's Shadowfugue

Target player discards two cards and loses 2 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Mind Ravel

Target player discards a card.
Draw a card at the beginning of the next turn's upkeep.

Stupor

Target opponent discards a card at random, then discards a card.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Horrifying Revelation

Target player discards a card, then mills a card.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Cruel Reality

Enchant player
At the beginning of enchanted player's upkeep, that player sacrifices a creature or planeswalker of their choice. If the player can't, they lose 5 life.

Dark Ritual

Festering Wound

Enchant creature
At the beginning of your upkeep, you may put an infection counter on Festering Wound.
At the beginning of the upkeep of enchanted creature's controller, Festering Wound deals X damage to that player, where X is the number of infection counters on Festering Wound.

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Tourach's Canticle

Target opponent reveals their hand. You choose a card from it. That player discards that card, then discards a card at random.

Mind Peel

Buyback {2}{B}{B} (You may pay an additional {2}{B}{B} as you cast this spell. If you do, put this card into your hand as it resolves.)
Target player discards a card.

Pilfer

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.

Infernal Darkness

Cumulative upkeep—Pay {B} and 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
If a land is tapped for mana, it produces {B} instead of any other type.

Distress

Target player reveals their hand. You choose a nonland card from it. That player discards that card.

Maga, Traitor to Mortals

Maga, Traitor to Mortals enters with X +1/+1 counters on it.
When Maga enters, target player loses life equal to the number of +1/+1 counters on it.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Remorseless Punishment

Target opponent loses 5 life unless that player discards two cards or sacrifices a creature or planeswalker of their choice. Repeat this process once.

Dingus Staff

Whenever a creature dies, Dingus Staff deals 2 damage to that creature's controller.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Unhinge

Target player discards a card.
Draw a card.

Drain Life

Spend only black mana on X.
Drain Life deals X damage to any target. You gain life equal to the damage dealt, but not more life than the player's life total before the damage was dealt, the planeswalker's loyalty before the damage was dealt, or the creature's toughness.

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

No Mercy

Whenever a creature deals damage to you, destroy it.

Wall of Souls

Defender (This creature can't attack.)
Whenever Wall of Souls is dealt combat damage, it deals that much damage to target opponent or planeswalker.

Unnerve

Death Cloud

Each player loses X life, discards X cards, sacrifices X creatures of their choice, then sacrifices X lands of their choice.

Three Tragedies

Nightsnare

Target opponent reveals their hand. You may choose a nonland card from it. If you do, that player discards that card. If you don't, that player discards two cards.

Wall of Vipers

Defender (This creature can't attack.)
{3}: Destroy Wall of Vipers and target creature it's blocking. Any player may activate this ability.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Delirium Skeins

Deception

Mind Drain

Target opponent discards two cards, mills a card, and loses 1 life. You gain 1 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Memory Leak

Target opponent reveals their hand. You choose a nonland card from that player's graveyard or hand and exile it.
Cycling {1} ({1}, Discard this card: Draw a card.)

Forbidden Ritual

Sacrifice a nontoken permanent. If you do, target opponent loses 2 life unless that player sacrifices a permanent of their choice or discards a card. You may repeat this process any number of times.

Banewasp Affliction

Enchant creature
When enchanted creature dies, that creature's controller loses life equal to its toughness.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Sickening Dreams

As an additional cost to cast this spell, discard X cards.
Sickening Dreams deals X damage to each creature and each player.

Encroach

Target player reveals their hand. You choose a nonbasic land card from it. That player discards that card.

Mind Rot

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Syphon Life

Target player loses 2 life and you gain 2 life.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Psychic Miasma

Target player discards a card. If a land card is discarded this way, return Psychic Miasma to its owner's hand.

Burden of Greed

Target player loses 1 life for each tapped artifact they control.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Hymn to Tourach

Target player discards two cards at random.

Dash Hopes

When you cast this spell, any player may pay 5 life. If a player does, counter Dash Hopes.
Counter target spell.

Ostracize

Target opponent reveals their hand. You choose a creature card from it. That player discards that card.

Wall of Shadows

Defender (This creature can't attack.)
Prevent all damage that would be dealt to Wall of Shadows by creatures it's blocking.
Wall of Shadows can't be the target of spells that can target only Walls or of abilities that can target only Walls.

Mind Warp

Look at target player's hand and choose X cards from it. That player discards those cards.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Wand of Vertebrae

{T}: Mill a card.
{2}, {T}, Exile Wand of Vertebrae: Shuffle up to five target cards from your graveyard into your library.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Haunting Hymn

Target player discards two cards. If you cast this spell during your main phase, that player discards four cards instead.

Essence Drain

Essence Drain deals 3 damage to any target and you gain 3 life.

Wrench Mind

Target player discards two cards unless they discard an artifact card.

Gibbering Barricade

Defender
{2}{B}, Sacrifice a creature: You gain 1 life and draw a card.

Soul Spike

You may exile two black cards from your hand rather than pay this spell's mana cost.
Soul Spike deals 4 damage to any target and you gain 4 life.

Wit's End

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Mind Twist

Invoke Despair

Target opponent sacrifices a creature of their choice. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Shatter Assumptions

Choose one —
• Target opponent reveals their hand and discards all colorless nonland cards.
• Target opponent reveals their hand and discards all multicolored cards.

Wall of Distortion

Defender (This creature can't attack.)
{2}{B}, {T}: Target player discards a card. Activate only as a sorcery.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.