Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Rotting Rats

When Rotting Rats enters, each player discards a card.
Unearth {1}{B} ({1}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker. Each player who can't discards a card.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Mindslicer

When Mindslicer dies, each player discards their hand.

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Virus Beetle

When Virus Beetle enters, each opponent discards a card.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Disentomb

Return target creature card from your graveyard to your hand.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Dread Return

Return target creature card from your graveyard to the battlefield.
Flashback—Sacrifice three creatures. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Cast Down

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Pilfer

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Mind Drain

Target opponent discards two cards, mills a card, and loses 1 life. You gain 1 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Oppression

Whenever a player casts a spell, that player discards a card.

Sol Ring

Fanatical Offering

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Map token. (It's an artifact with "{1}, {T}, Sacrifice this artifact: Target creature you control explores. Activate only as a sorcery.")

Eriette's Whisper

Target opponent discards two cards. Create a Wicked Role token attached to up to one target creature you control. (If you control another Role on it, put that one into the graveyard. Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

Sorcerous Spyglass

As Sorcerous Spyglass enters, look at an opponent's hand, then choose any card name.
Activated abilities of sources with the chosen name can't be activated unless they're mana abilities.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Extract the Truth

Choose one —
• Target opponent reveals their hand. You may choose a creature, enchantment, or planeswalker card from it. That player discards that card.
• Target opponent sacrifices an enchantment.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Burglar Rat

When Burglar Rat enters, each opponent discards a card.

Temple of the Dead

(Transforms from Aclazotz, Deepest Betrayal.)
{T}: Add {B}.
{2}{B}, {T}: Transform Temple of the Dead. Activate only if a player has one or fewer cards in hand and only as a sorcery.

Aclazotz, Deepest Betrayal

Flying, lifelink
Whenever Aclazotz attacks, each opponent discards a card. For each opponent who can't, you draw a card.
Whenever an opponent discards a land card, create a 1/1 black Bat creature token with flying.
When Aclazotz dies, return it to the battlefield tapped and transformed under its owner's control.

Aclazotz, Deepest Betrayal // Temple of the Dead

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Nyxathid

As Nyxathid enters, choose an opponent.
Nyxathid gets -1/-1 for each card in the chosen player's hand.

Swamp

Stronghold Rats

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever Stronghold Rats deals combat damage to a player, each player discards a card.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Reassembling Skeleton

{1}{B}: Return Reassembling Skeleton from your graveyard to the battlefield tapped.

Bloodhusk Ritualist

Multikicker {B} (You may pay an additional {B} any number of times as you cast this spell.)
When Bloodhusk Ritualist enters, target opponent discards a card for each time it was kicked.

Raise Dead

Skullslither Worm

When Skullslither Worm enters, each opponent discards a card. For each opponent who can't, put two +1/+1 counters on Skullslither Worm.

Durable Coilbug

{4}{B}: Return Durable Coilbug from your graveyard to your hand.

Cult Conscript

Cult Conscript enters tapped.
{1}{B}: Return Cult Conscript from your graveyard to the battlefield. Activate only if a non-Skeleton creature died under your control this turn.

Dash Hopes

When you cast this spell, any player may pay 5 life. If a player does, counter Dash Hopes.
Counter target spell.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Urborg Scavengers

Whenever Urborg Scavengers enters or attacks, exile target card from a graveyard. Put a +1/+1 counter on Urborg Scavengers.
Urborg Scavengers has flying as long as a card exiled with it has flying. The same is true for first strike, double strike, deathtouch, haste, hexproof, indestructible, lifelink, menace, reach, trample, and vigilance.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Delirium Skeins

Fill with Fright

Target player discards two cards. Scry 2. (Look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Prickle Faeries

Flying
At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, Prickle Faeries deals 2 damage to them.

Invasion of Eldraine

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Eldraine enters, target opponent discards two cards.

Invasion of Eldraine // Prickle Faeries

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Go for the Throat

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.