Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Wrath of God

Destroy all creatures. They can't be regenerated.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Reckless Endeavor

Roll two d12 and choose one result. Reckless Endeavor deals damage equal to that result to each creature. Then create a number of Treasure tokens equal to the other result.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Aetherspouts

For each attacking creature, its owner puts it on their choice of the top or bottom of their library.

Damnation

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Promise of Loyalty

Each player puts a vow counter on a creature they control and sacrifices the rest. Each of those creatures can't attack you or planeswalkers you control for as long as it has a vow counter on it.

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Ondu Skyruins

Ondu Skyruins enters tapped.
{T}: Add {W}.

Ondu Inversion

Ondu Inversion // Ondu Skyruins

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Whelming Wave

Return all creatures to their owners' hands except for Krakens, Leviathans, Octopuses, and Serpents.

Perplexing Test

Choose one —
• Return all creature tokens to their owners' hands.
• Return all nontoken creatures to their owners' hands.

Winds of Abandon

Exile target creature you don't control. For each creature exiled this way, its controller searches their library for a basic land card. Those players put those cards onto the battlefield tapped, then shuffle.
Overload {4}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Curse of the Swine

Exile X target creatures. For each creature exiled this way, its controller creates a 2/2 green Boar creature token.

Day of Judgment

Plague Boiler

At the beginning of your upkeep, put a plague counter on Plague Boiler.
{1}{B}{G}: Put a plague counter on Plague Boiler or remove a plague counter from it.
When Plague Boiler has three or more plague counters on it, sacrifice it. If you do, destroy all nonland permanents.

Vandalblast

Destroy target artifact you don't control.
Overload {4}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Aetherize

Return all attacking creatures to their owner's hand.

Culling Ritual

Destroy each nonland permanent with mana value 2 or less. Add {B} or {G} for each permanent destroyed this way.