Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Curse of the Swine

Exile X target creatures. For each creature exiled this way, its controller creates a 2/2 green Boar creature token.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Nyx Lotus

Nyx Lotus enters tapped.
{T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Damnable Pact

Target player draws X cards and loses X life.

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Undead Alchemist

If a Zombie you control would deal combat damage to a player, instead that player mills that many cards.
Whenever a creature card is put into an opponent's graveyard from their library, exile that card and create a 2/2 black Zombie creature token.

Liliana's Specter

Flying
When Liliana's Specter enters, each opponent discards a card.

Maddening Cacophony

Kicker {3}{U}
Each opponent mills eight cards. If this spell was kicked, instead each opponent mills half their library, rounded up.

Clockwork Fox

When Clockwork Fox leaves the battlefield, you draw two cards and each opponent draws a card.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Blood Pact

Target player draws two cards and loses 2 life.

Rakshasa Debaser

Whenever Rakshasa Debaser attacks, put target creature card from defending player's graveyard onto the battlefield under your control.
Encore {6}{B}{B} ({6}{B}{B}, Exile this card from your graveyard: For each opponent, create a token copy that attacks that opponent this turn if able. They gain haste. Sacrifice them at the beginning of the next end step. Activate only as a sorcery.)

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Harvester of Souls

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever another nontoken creature dies, you may draw a card.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Counterspell

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Jace, Memory Adept

+1: Draw a card. Target player mills a card.
0: Target player mills ten cards.
−7: Any number of target players each draw twenty cards.

Arcane Denial

Counter target spell. Its controller may draw up to two cards at the beginning of the next turn's upkeep.
You draw a card at the beginning of the next turn's upkeep.

Keening Stone

{5}, {T}: Target player mills X cards, where X is the number of cards in that player's graveyard.

Howling Golem

Whenever Howling Golem attacks or blocks, each player draws a card.

Magus of the Coffers

{2}, {T}: Add {B} for each Swamp you control.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

The Mycosynth Gardens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.
{X}, {T}: The Mycosynth Gardens becomes a copy of target nontoken artifact you control with mana value X.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Cut Your Losses

Casualty 2 (As you cast this spell, you may sacrifice a creature with power 2 or greater. When you do, copy this spell and you may choose a new target for the copy.)
Target player mills half their library, rounded down.

Sign in Blood

Atrocious Experiment

Target player mills two cards, draws two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Teferi's Tutelage

When Teferi's Tutelage enters, draw a card, then discard a card.
Whenever you draw a card, target opponent mills two cards. (They put the top two cards of their library into their graveyard.)

Urgoros, the Empty One

Flying
Whenever Urgoros, the Empty One deals combat damage to a player, that player discards a card at random. If the player can't, you draw a card.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Temple Bell

Bruvac the Grandiloquent

If an opponent would mill one or more cards, they mill twice that many cards instead. (To mill a card, a player puts the top card of their library into their graveyard.)

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Price of Knowledge

Players have no maximum hand size.
At the beginning of each opponent's upkeep, Price of Knowledge deals damage to that player equal to the number of cards in that player's hand.

Sepulchral Primordial

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
When Sepulchral Primordial enters, for each opponent, you may put up to one target creature card from that player's graveyard onto the battlefield under your control.

Liliana, Defiant Necromancer

+2: Each player discards a card.
−X: Return target nonlegendary creature card with mana value X from your graveyard to the battlefield.
−8: You get an emblem with "Whenever a creature dies, return it to the battlefield under your control at the beginning of the next end step."

Liliana, Heretical Healer

Lifelink
Whenever another nontoken creature you control dies, exile Liliana, Heretical Healer, then return her to the battlefield transformed under her owner's control. If you do, create a 2/2 black Zombie creature token.

Liliana, Heretical Healer // Liliana, Defiant Necromancer

Gnat Miser

Each opponent's maximum hand size is reduced by one.

Persistent Petitioners

{1}, {T}: Target player mills a card. (They put the top card of their library into their graveyard.)
Tap four untapped Advisors you control: Target player mills twelve cards.
A deck can have any number of cards named Persistent Petitioners.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Silent Arbiter

No more than one creature can attack each combat.
No more than one creature can block each combat.

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice Hedron Archive: Draw two cards.

Didn't Say Please

Counter target spell. Its controller mills three cards.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Fractured Sanity

Each opponent mills fourteen cards.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Fractured Sanity, each opponent mills four cards.

Kami of the Crescent Moon

At the beginning of each player's draw step, that player draws an additional card.

Thought Collapse

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Increasing Confusion

Target player mills X cards. If this spell was cast from a graveyard, that player mills twice that many cards instead.
Flashback {X}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Persistent Nightmare

Skulk (This creature can't be blocked by creatures with greater power.)
When Persistent Nightmare deals combat damage to a player, return it to its owner's hand.

Startled Awake

Target opponent mills thirteen cards.
{3}{U}{U}: Put Startled Awake from your graveyard onto the battlefield transformed. Activate only as a sorcery.

Startled Awake // Persistent Nightmare

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Island

Fraying Sanity

Enchant player
At the beginning of each end step, enchanted player mills X cards, where X is the number of cards put into their graveyard from anywhere this turn.

Locust Miser

Each opponent's maximum hand size is reduced by two.

Harrowing Journey

Target player draws three cards and loses 3 life.

Otherworld Atlas

{T}: Put a charge counter on Otherworld Atlas.
{T}: Each player draws a card for each charge counter on Otherworld Atlas.

Stonespeaker Crystal

{T}: Add {C}{C}.
{2}, {T}, Sacrifice Stonespeaker Crystal: Exile any number of target players' graveyards. Draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Caged Sun

As Caged Sun enters, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add one additional mana of that color.

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Arcanis the Omnipotent

{T}: Draw three cards.
{2}{U}{U}: Return Arcanis the Omnipotent to its owner's hand.

Traumatize

Target player mills half their library, rounded down.

Runed Servitor

When Runed Servitor dies, each player draws a card.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.