Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Razaketh, the Foulblooded

Flying, trample
Pay 2 life, Sacrifice another creature: Search your library for a card, put that card into your hand, then shuffle.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Apex of Power

Exile the top seven cards of your library. Until end of turn, you may cast spells from among them.
If this spell was cast from your hand, add ten mana of any one color.

Foreboding Ruins

As Foreboding Ruins enters, you may reveal a Swamp or Mountain card from your hand. If you don't, Foreboding Ruins enters tapped.
{T}: Add {B} or {R}.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Sign in Blood

Target player draws two cards and loses 2 life.

Electrodominance

Electrodominance deals X damage to any target. You may cast a spell with mana value X or less from your hand without paying its mana cost.

Damnable Pact

Target player draws X cards and loses X life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Comet Storm

Multikicker {1} (You may pay an additional {1} any number of times as you cast this spell.)
Choose any target, then choose another target for each time this spell was kicked. Comet Storm deals X damage to each of them.

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Arcane Signet

Call Forth the Tempest

Cascade, cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom of your library in a random order. Then do it again.)
Call Forth the Tempest deals damage to each creature your opponents control equal to the total mana value of other spells you've cast this turn.

Banefire

Banefire deals X damage to any target.
If X is 5 or more, this spell can't be countered and the damage can't be prevented.

Ambition's Cost

You draw three cards and you lose 3 life.

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Profane Command

Choose two —
• Target player loses X life.
• Return target creature card with mana value X or less from your graveyard to the battlefield.
• Target creature gets -X/-X until end of turn.
• Up to X target creatures gain fear until end of turn. (They can't be blocked except by artifact creatures and/or black creatures.)

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Temple of Malice

Temple of Malice enters tapped.
When Temple of Malice enters, scry 1.
{T}: Add {B} or {R}.

Expensive Taste

Exile the top two cards of target opponent's library face down. You may look at and play those cards for as long as they remain exiled.

Decadent Dragon

Flying, trample
Whenever Decadent Dragon attacks, create a Treasure token.

Decadent Dragon // Expensive Taste

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Swamp

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Infernal Grasp

Destroy target creature. You lose 2 life.

Storm King's Thunder

When you next cast an instant or sorcery spell this turn, copy that spell X times. You may choose new targets for the copies.

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Battle at the Bridge

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Target creature gets -X/-X until end of turn. You gain X life.

Rowan, Scion of War

Menace
{T}: Spells you cast this turn that are black and/or red cost {X} less to cast, where X is the amount of life you lost this turn. Activate only as a sorcery.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Thrill of Possibility

As an additional cost to cast this spell, discard a card.
Draw two cards.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Immolating Souleater

{R/P}: Immolating Souleater gets +1/+0 until end of turn. ({R/P} can be paid with either {R} or 2 life.)

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Bloodfell Caves

Bloodfell Caves enters tapped.
When Bloodfell Caves enters, you gain 1 life.
{T}: Add {B} or {R}.

Hell to Pay

Hell to Pay deals X damage to target creature. Create a number of tapped Treasure tokens equal to the amount of excess damage dealt to that creature this way.

Rakdos Carnarium

Rakdos Carnarium enters tapped.
When Rakdos Carnarium enters, return a land you control to its owner's hand.
{T}: Add {B}{R}.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Orcus, Prince of Undeath

Flying, trample
When Orcus, Prince of Undeath enters, choose one —
• Each other creature gets -X/-X until end of turn. You lose X life.
• Return up to X target creature cards with total mana value X or less from your graveyard to the battlefield. They gain haste until end of turn.

Bitter Triumph

As an additional cost to cast this spell, discard a card or pay 3 life.
Destroy target creature or planeswalker.

Shadowblood Ridge

Dark Tutelage

Tibalt's Trickery

Counter target spell. Choose 1, 2, or 3 at random. Its controller mills that many cards, then exiles cards from the top of their library until they exile a nonland card with a different name than that spell. They may cast that card without paying its mana cost. Then they put the exiled cards on the bottom of their library in a random order.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Infernal Sovereign

Flying, trample
Skip your draw step.
Whenever you play a land or cast a spell, you draw a card and you lose 1 life.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Greed

Blood Pact

Shard of the Nightbringer

Flying
Drain Life — When Shard of the Nightbringer enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Mountain

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Akoum Refuge

Akoum Refuge enters tapped.
When Akoum Refuge enters, you gain 1 life.
{T}: Add {B} or {R}.

Terminate

Destroy target creature. It can't be regenerated.

Souldrinker

Pay 3 life: Put a +1/+1 counter on Souldrinker.

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Shivan Devastator

Flying, haste
Shivan Devastator enters with X +1/+1 counters on it.

Swallowing Plague

Swallowing Plague deals X damage to target creature and you gain X life.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Vandalblast

Destroy target artifact you don't control.
Overload {4}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Greven, Predator Captain

Menace
Greven, Predator Captain gets +X/+0, where X is the amount of life you've lost this turn.
Whenever Greven attacks, you may sacrifice another creature. If you do, you draw cards equal to that creature's power and you lose life equal to that creature's toughness.

Professor Onyx

Magecraft — Whenever you cast or copy an instant or sorcery spell, each opponent loses 2 life and you gain 2 life.
+1: You lose 1 life. Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
−3: Each opponent sacrifices a creature with the greatest power among creatures that player controls.
−8: Each opponent may discard a card. If they don't, they lose 3 life. Repeat this process six more times.