Grinning Demon

At the beginning of your upkeep, you lose 2 life.
Morph {2}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Soulgorger Orgg

Trample
When Soulgorger Orgg enters, you lose all but 1 life.
When Soulgorger Orgg leaves the battlefield, you gain life equal to the life you lost when it entered.

Copper Tablet

At the beginning of each player's upkeep, Copper Tablet deals 1 damage to that player.

Wretched Anurid

Whenever another creature enters, you lose 1 life.

Relic Bane

Enchant artifact
Enchanted artifact has "At the beginning of your upkeep, you lose 2 life."