Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Swamp

Grimdancer

Grimdancer enters with your choice of two different counters on it from among menace, deathtouch, and lifelink.

Festering Goblin

When Festering Goblin dies, target creature gets -1/-1 until end of turn.

Ancestral Vengeance

Enchant creature
When Ancestral Vengeance enters, put a +1/+1 counter on target creature you control.
Enchanted creature gets -1/-1.

Breaker of Armies

All creatures able to block Breaker of Armies do so.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Black Dragon

Flying
Acid Breath — When Black Dragon enters, target creature an opponent controls gets -3/-3 until end of turn.

Dreamspoiler Witches

Flying
Whenever you cast a spell during an opponent's turn, you may have target creature get -1/-1 until end of turn.

Grasp of Darkness

Target creature gets -4/-4 until end of turn.

Triarch Stalker

Targeting Relay — At the beginning of combat on your turn, choose an opponent.
Creatures attacking the last chosen player have menace.

Reaper of Sheoldred

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever a source deals damage to Reaper of Sheoldred, that source's controller gets a poison counter.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Commander's Plate

Equipped creature gets +3/+3 and has protection from each color that's not in your commander's color identity.
Equip commander {3}
Equip {5}

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Eyes of the Beholder

Target creature gets -11/-11 until end of turn.

Battle at the Bridge

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Target creature gets -X/-X until end of turn. You gain X life.

Fevered Convulsions

{2}{B}{B}: Put a -1/-1 counter on target creature.

Drivnod, Carnage Dominus

If a creature dying causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.
{B/P}{B/P}, Exile three creature cards from your graveyard: Put an indestructible counter on Drivnod, Carnage Dominus. ({B/P} can be paid with either {B} or 2 life.)

Lash of Malice

Target creature gets +2/-2 until end of turn.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Cadaverous Knight

Flanking (Whenever a creature without flanking blocks this creature, the blocking creature gets -1/-1 until end of turn.)
{1}{B}{B}: Regenerate Cadaverous Knight.

Grave Betrayal

Whenever a creature you don't control dies, return it to the battlefield under your control with an additional +1/+1 counter on it at the beginning of the next end step. That creature is a black Zombie in addition to its other colors and types.

Afflict

Target creature gets -1/-1 until end of turn.
Draw a card.

Bile Blight

Target creature and all other creatures with the same name as that creature get -3/-3 until end of turn.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.

Drana, Kalastria Bloodchief

Flying
{X}{B}{B}: Target creature gets -0/-X until end of turn and Drana, Kalastria Bloodchief gets +X/+0 until end of turn.

Shadow Rider

Flanking (Whenever a creature without flanking blocks this creature, the blocking creature gets -1/-1 until end of turn.)

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Abattoir Ghoul

First strike
Whenever a creature dealt damage by Abattoir Ghoul this turn dies, you gain life equal to that creature's toughness.

Plague Wight

Whenever Plague Wight becomes blocked, each creature blocking it gets -1/-1 until end of turn.

Wurmcoil Engine

Deathtouch, lifelink
When Wurmcoil Engine dies, create a 3/3 colorless Phyrexian Wurm artifact creature token with deathtouch and a 3/3 colorless Phyrexian Wurm artifact creature token with lifelink.

Nemesis Mask

All creatures able to block equipped creature do so.
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery. This card enters unattached and stays on the battlefield if the creature leaves.)

Fallen Askari

Flanking (Whenever a creature without flanking blocks this creature, the blocking creature gets -1/-1 until end of turn.)
Fallen Askari can't block.

Blister Beetle

When Blister Beetle enters, target creature gets -1/-1 until end of turn.

Plague Mare

Plague Mare can't be blocked by white creatures.
When Plague Mare enters, creatures your opponents control get -1/-1 until end of turn.

Midnight Banshee

Wither (This deals damage to creatures in the form of -1/-1 counters.)
At the beginning of your upkeep, put a -1/-1 counter on each nonblack creature.

Nesting Grounds

{T}: Add {C}.
{1}, {T}: Move a counter from target permanent you control onto another target permanent. Activate only as a sorcery.

Shard of the Void Dragon

Flying
Spear of the Void Dragon — Whenever Shard of the Void Dragon attacks, each opponent sacrifices a nonland permanent.
Matter Absorption — Whenever an artifact is put into a graveyard from the battlefield or is put into exile from the battlefield, put two +1/+1 counters on Shard of the Void Dragon.

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Orc Sureshot

Whenever another creature you control enters, target creature an opponent controls gets -1/-1 until end of turn.

Shard of the Nightbringer

Flying
Drain Life — When Shard of the Nightbringer enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Baneclaw Marauder

Whenever Baneclaw Marauder becomes blocked, each creature blocking it gets -1/-1 until end of turn.
Whenever a creature blocking Baneclaw Marauder dies, that creature's controller loses 1 life.
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Baneblade Scoundrel

Whenever Baneblade Scoundrel becomes blocked, each creature blocking it gets -1/-1 until end of turn.
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Baneblade Scoundrel // Baneclaw Marauder

Nefashu

Whenever Nefashu attacks, up to five target creatures each get -1/-1 until end of turn.

Spitting Dilophosaurus

Whenever Spitting Dilophosaurus enters or attacks, put a -1/-1 counter on up to one target creature.
Creatures your opponents control with -1/-1 counters on them can't block.

Nimraiser Paladin

Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)
When Nimraiser Paladin enters, return target creature card with mana value 3 or less from your graveyard to your hand.

Skinrender

When Skinrender enters, put three -1/-1 counters on target creature.

Massacre Girl, Known Killer

Menace
Creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls dies, if its toughness was less than 1, draw a card.

Nurgle's Rot

Enchant creature an opponent controls
When enchanted creature dies, return Nurgle's Rot to its owner's hand and you create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Whack

This spell costs {3} less to cast if it targets a white creature.
Target creature gets -4/-4 until end of turn.

Lockjaw Snapper

Wither (This deals damage to creatures in the form of -1/-1 counters.)
When Lockjaw Snapper dies, put a -1/-1 counter on each creature with a -1/-1 counter on it.

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Arms of Hadar

Creatures target player controls get -2/-2 until end of turn.

Kozilek, Butcher of Truth

When you cast this spell, draw four cards.
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents.)
When Kozilek, Butcher of Truth is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Yargle, Glutton of Urborg

Sadistic Obsession

Enchant creature
Enchanted creature has "{B}, {T}: Put a -1/-1 counter on target creature."

Instill Infection

Put a -1/-1 counter on target creature.
Draw a card.

Etched Familiar

When Etched Familiar dies, each opponent loses 2 life and you gain 2 life.

Strip Mine

{T}: Add {C}.
{T}, Sacrifice Strip Mine: Destroy target land.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Grim Poppet

Grim Poppet enters with three -1/-1 counters on it.
Remove a -1/-1 counter from Grim Poppet: Put a -1/-1 counter on another target creature.

Virulent Wound

Put a -1/-1 counter on target creature. When that creature dies this turn, its controller gets a poison counter.

Bleeding Edge

Up to one target creature gets -2/-2 until end of turn. Amass Zombies 2. (Put two +1/+1 counters on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)

Arco-Flagellant

Squad {2} (As an additional cost to cast this spell, you may pay {2} any number of times. When this creature enters, create that many tokens that are copies of it.)
Arco-Flagellant can't block.
Endurant — Pay 3 life: Arco-Flagellant gains indestructible until end of turn.

Black Sun's Twilight

Up to one target creature gets -X/-X until end of turn. If X is 5 or more, return a creature card with mana value X or less from your graveyard to the battlefield tapped.

Sol Ring

Echoing Decay

Target creature and all other creatures with the same name as that creature get -2/-2 until end of turn.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Blightbeetle

Protection from green (This creature can't be blocked, targeted, dealt damage, enchanted, or equipped by anything green.)
Creatures your opponents control can't have +1/+1 counters put on them.

Primaris Eliminator

When Primaris Eliminator enters, choose one —
• Executioner Round — Destroy target creature.
• Hyperfrag Round — Creatures target player controls get -2/-2 until end of turn.

Incremental Blight

Put a -1/-1 counter on target creature, two -1/-1 counters on another target creature, and three -1/-1 counters on a third target creature.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Fume Spitter

Sacrifice Fume Spitter: Put a -1/-1 counter on target creature.

Sudden Death

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Target creature gets -4/-4 until end of turn.

Candy Grapple

Bargain (You may sacrifice an artifact, enchantment, or token as you cast this spell.)
Target creature gets -3/-3 until end of turn. If this spell was bargained, that creature gets -5/-5 until end of turn instead.

Sword of the Animist

Equipped creature gets +1/+1.
Whenever equipped creature attacks, you may search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
Equip {2}

Midnight Recovery

Return target creature card from your graveyard to your hand.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Festering Mummy

When Festering Mummy dies, you may put a -1/-1 counter on target creature.

Darkblast

Target creature gets -1/-1 until end of turn.
Dredge 3 (If you would draw a card, you may mill three cards instead. If you do, return this card from your graveyard to your hand.)

Bloodline Culling

Choose one —
• Target creature gets -5/-5 until end of turn.
• Creature tokens get -2/-2 until end of turn.

Sword of Truth and Justice

Equipped creature gets +2/+2 and has protection from white and from blue.
Whenever equipped creature deals combat damage to a player, put a +1/+1 counter on a creature you control, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Equip {2}

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Crumbling Ashes

At the beginning of your upkeep, destroy target creature with a -1/-1 counter on it.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Phyrexian Plaguelord

{T}, Sacrifice Phyrexian Plaguelord: Target creature gets -4/-4 until end of turn.
Sacrifice a creature: Target creature gets -1/-1 until end of turn.