Maybe

Feed the Infection

You draw three cards and you lose 3 life.
Corrupted — Each opponent who has three or more poison counters loses 3 life.

Possibly

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard this card: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Kitchen Imp

Flying, haste
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Don't Have

Ifnir Deadlands

{T}: Add {C}.
{T}, Pay 1 life: Add {B}.
{2}{B}{B}, {T}, Sacrifice a Desert: Put two -1/-1 counters on target creature an opponent controls. Activate only as a sorcery.

Pitiless Vizier

Whenever you cycle or discard a card, this creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it. If its toughness is 0 or less, it's still put into its owner's graveyard.)

Harvester of Souls

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever another nontoken creature dies, you may draw a card.

Argentum Masticore

First strike, protection from multicolored
At the beginning of your upkeep, sacrifice this creature unless you discard a card. When you discard a card this way, destroy target nonland permanent an opponent controls with mana value less than or equal to the mana value of the discarded card.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Blightwing Whelp

Flying
Toxic 1
{B}: Blightwing Whelp gains haste until end of turn.
Whenever Blightwing Whelp deals combat damage to a player, seek a card with mana value equal to the number of poison counters that player has.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Shadows' Lair

(Transforms from Grasping Shadows.)
{T}: Add {B}.
{B}, {T}, Remove a dread counter from this land: You draw a card and you lose 1 life.

Have

Grasping Shadows

Whenever a creature you control attacks alone, it gains deathtouch and lifelink until end of turn. Put a dread counter on this enchantment. Then if there are three or more dread counters on it, transform it.

Grasping Shadows // Shadows' Lair

Fleshless Gladiator

Corrupted — {2}{B}: Return this card from your graveyard to the battlefield tapped. You lose 1 life. Activate only if an opponent has three or more poison counters.

Rat Out

Up to one target creature gets -1/-1 until end of turn. You create a 1/1 black Rat creature token with "This token can't block."

Eaten Alive

As an additional cost to cast this spell, sacrifice a creature or pay {3}{B}.
Exile target creature or planeswalker.

Getting

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Corrupt

Corrupt deals damage to any target equal to the number of Swamps you control. You gain life equal to the damage dealt this way.

Drana, Liberator of Malakir

Flying, first strike
Whenever Drana deals combat damage to a player, put a +1/+1 counter on each attacking creature you control.

Phyrexian Rager

When this creature enters, you draw a card and you lose 1 life.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Creeping Inn

Whenever this creature attacks, you may exile a creature card from your graveyard. If you do, each opponent loses X life and you gain X life, where X is the number of creature cards exiled with this creature.
{4}: This creature phases out.

Hostile Hostel

{T}: Add {C}.
{1}, {T}, Sacrifice a creature: Put a soul counter on this land. Then if there are three or more soul counters on it, remove those counters, transform it, then untap it. Activate only as a sorcery.

Hostile Hostel // Creeping Inn

Phyrexian Fleshgorger

Prototype {1}{B}{B} — 3/3 (You may cast this spell with different mana cost, color, and size. It keeps its abilities and types.)
Menace, lifelink
Ward—Pay life equal to this creature's power.

Ruthless Sniper

Whenever you cycle or discard a card, you may pay {1}. If you do, put a -1/-1 counter on target creature.

Dying to Serve

Whenever you discard one or more cards, create a tapped 2/2 black Zombie creature token. This ability triggers only once each turn.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Call of the Ring

At the beginning of your upkeep, the Ring tempts you.
Whenever you choose a creature as your Ring-bearer, you may pay 2 life. If you do, draw a card.

Dreadhound

When this creature enters, mill three cards. (Put the top three cards of your library into your graveyard.)
Whenever a creature dies or a creature card is put into a graveyard from a library, each opponent loses 1 life.

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Rogue's Gloves

Whenever equipped creature deals combat damage to a player, you may draw a card.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Gift of Compleation

When this enchantment enters, incubate 3. (Create an Incubator token with three +1/+1 counters on it and "{2}: Transform this token." It transforms into a 0/0 Phyrexian artifact creature.)
Whenever a Phyrexian you control dies, surveil 1. (Look at the top card of your library. You may put that card into your graveyard.)

Roadside Reliquary

{T}: Add {C}.
{2}, {T}, Sacrifice this land: Draw a card if you control an artifact. Draw a card if you control an enchantment.

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Tarrian's Soulcleaver

Equipped creature has vigilance.
Whenever another artifact or creature is put into a graveyard from the battlefield, put a +1/+1 counter on equipped creature.
Equip {2}

Grim Haruspex

Morph {B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
Whenever another nontoken creature you control dies, draw a card.

The True Scriptures

(As this Saga enters and after your draw step, add a lore counter.)
I — For each opponent, destroy up to one target creature or planeswalker that player controls.
II — Each opponent discards three cards, then mills three cards.
III — Put all creature cards from all graveyards onto the battlefield under your control. Exile this Saga, then return it to the battlefield (front face up).

Sheoldred

Menace
When Sheoldred enters, each opponent sacrifices a nontoken creature or planeswalker of their choice.
{4}{B}: Exile Sheoldred, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if an opponent has eight or more cards in their graveyard.

Sheoldred // The True Scriptures

Kaervek, the Spiteful

Lord Skitter's Blessing

When this enchantment enters, create a Wicked Role token attached to target creature you control. (Enchanted creature gets +1/+1. When this token is put into a graveyard, each opponent loses 1 life.)
At the beginning of your draw step, if you control an enchanted creature, you lose 1 life and you draw an additional card.

Bone Splinters

As an additional cost to cast this spell, sacrifice a creature.
Destroy target creature.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Necrosquito

Flying
This creature enters with two oil counters on it.
This creature gets +1/+1 for each oil counter on it.
Whenever another creature or artifact you control is put into a graveyard from the battlefield, put an oil counter on this creature.

Lich-Knights' Conquest

Sacrifice any number of artifacts, enchantments, and/or tokens. Return that many creature cards from your graveyard to the battlefield.

Troll of Khazad-dûm

This creature can't be blocked except by three or more creatures.
Swampcycling {1} ({1}, Discard this card: Search your library for a Swamp card, reveal it, put it into your hand, then shuffle.)

Liliana's Contract

When this enchantment enters, you draw four cards and you lose 4 life.
At the beginning of your upkeep, if you control four or more Demons with different names, you win the game.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Reckoner's Bargain

As an additional cost to cast this spell, sacrifice an artifact or creature.
You gain life equal to the sacrificed permanent's mana value. Draw two cards.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Stinging Cave Crawler

Deathtouch
Descend 4 — Whenever this creature attacks, if there are four or more permanent cards in your graveyard, you draw a card and you lose 1 life.

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Transmogrant's Crown

Equipped creature gets +2/+0.
Whenever equipped creature dies, draw a card.
Equip {2} or {B}

Sheoldred's Assimilator

Menace
Whenever Sheoldred's Assimilator enters or attacks, exile up to one target card from a graveyard. If a card is exiled this way, you may conjure a duplicate of that card into the top five cards of your library at random.

March Toward Perfection

You get a one-time boon with "When you cast a Phyrexian creature spell, that creature enters with an additional +1/+1 counter and deathtouch counter on it."
Draft a card from March Toward Perfection's spellbook.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Locthwain Scorn

Target creature gets -3/-3 until end of turn. You gain 2 life.

Virtue of Persistence

At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control.

Virtue of Persistence // Locthwain Scorn

Ribskiff

Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)
When this Vehicle enters, draw a card.
Crew 3 (Tap any number of creatures you control with total power 3 or more: This Vehicle becomes an artifact creature until end of turn.)

Ayara, First of Locthwain

Whenever Ayara or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Mirrodin Avenged

Destroy target creature that was dealt damage this turn.
Draw a card.

Faith of the Devoted

Whenever you cycle or discard a card, you may pay {1}. If you do, each opponent loses 2 life and you gain 2 life.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Crystal Grotto

When this land enters, scry 1.
{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Dreadfeast Demon

Flying
At the beginning of your end step, sacrifice a non-Demon creature. If you do, create a token that's a copy of this creature.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When this creature dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Bonepicker Skirge

Flying
Corrupted — As long as an opponent has three or more poison counters, this creature has deathtouch and lifelink.

Barren Moor

This land enters tapped.
{T}: Add {B}.
Cycling {B} ({B}, Discard this card: Draw a card.)

Revealing Eye

Menace
When this creature transforms into Revealing Eye, target opponent reveals their hand. You may choose a nonland card from it. If you do, that player discards that card, then draws a card.

Concealing Curtains

Defender
{2}{B}: Transform this creature. Activate only as a sorcery.

Concealing Curtains // Revealing Eye

Pestilent Syphoner

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Malefic Scythe

This Equipment enters with a soul counter on it.
Equipped creature gets +1/+1 for each soul counter on this Equipment.
Whenever equipped creature dies, put a soul counter on this Equipment.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap this artifact.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Bringer of the Last Gift

Flying
When this creature enters, if you cast it, each player sacrifices all other creatures they control. Then each player returns all creature cards from their graveyard that weren't put there this way to the battlefield.

Diabolic Intent

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card, put that card into your hand, then shuffle.

Carnifex Demon

Flying
This creature enters with two -1/-1 counters on it.
{B}, Remove a -1/-1 counter from this creature: Put a -1/-1 counter on each other creature.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Nightmare

Flying (This creature can't be blocked except by creatures with flying or reach.)
Nightmare's power and toughness are each equal to the number of Swamps you control.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This token can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Chittering Skitterling

Corrupted — Sacrifice an artifact or creature: Draw a card. Activate only if an opponent has three or more poison counters and only once each turn.

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Sewer Plague

Target creature an opponent controls perpetually gets -2/-2 and gains "At the beginning of each upkeep, this creature perpetually gets -1/-1."

Gulping Scraptrap

When this creature enters or dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ravenous Necrotitan

Corrupted — When this creature enters, sacrifice a creature unless an opponent has three or more poison counters.

Zephyr Boots

Equipped creature has flying.
Whenever equipped creature deals combat damage to a player, draw a card, then discard a card.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Uncharted Haven

This land enters tapped. As it enters, choose a color.
{T}: Add one mana of the chosen color.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Gurgling Anointer

Flying
Whenever you draw your second card each turn, put a +1/+1 counter on this creature.
When this creature dies, return another target creature card with mana value less than or equal to this creature's power from your graveyard to the battlefield.