Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Melira, the Living Cure

If you would get one or more poison counters, instead you get one poison counter and you can't get additional poison counters this turn.
Exile Melira, the Living Cure: Choose another target creature or artifact. When it's put into a graveyard this turn, return that card to the battlefield under its owner's control.