Cut Your Losses

Casualty 2 (As you cast this spell, you may sacrifice a creature with power 2 or greater. When you do, copy this spell and you may choose a new target for the copy.)
Target player mills half their library, rounded down.

Invoke Despair

Target opponent sacrifices a creature of their choice. If they can't, they lose 2 life and you draw a card. Then repeat this process for an enchantment and a planeswalker.

Gloomlake Verge

{T}: Add {U}.
{T}: Add {B}. Activate only if you control an Island or a Swamp.

Tasha's Hideous Laughter

Each opponent exiles cards from the top of their library until that player has exiled cards with total mana value 20 or more.

Fraying Sanity

Enchant player
At the beginning of each end step, enchanted player mills X cards, where X is the number of cards put into their graveyard from anywhere this turn.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Consuming Aberration

Consuming Aberration's power and toughness are each equal to the number of cards in your opponents' graveyards.
Whenever you cast a spell, each opponent reveals cards from the top of their library until they reveal a land card, then puts those cards into their graveyard.

Infernal Grasp

Destroy target creature. You lose 2 life.

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Blood Beckoning

Kicker {3} (You may pay an additional {3} as you cast this spell.)
Return target creature card from your graveyard to your hand. If this spell was kicked, instead return two target creature cards from your graveyard to your hand.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Nighthowler

Bestow {2}{B}{B} (If you cast this card for its bestow cost, it's an Aura spell with enchant creature. It becomes a creature again if it's not attached to a creature.)
Nighthowler and enchanted creature each get +X/+X, where X is the number of creature cards in all graveyards.

Dimir Aqueduct

Dimir Aqueduct enters tapped.
When Dimir Aqueduct enters, return a land you control to its owner's hand.
{T}: Add {U}{B}.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Sewer Nemesis

As Sewer Nemesis enters, choose a player.
Sewer Nemesis's power and toughness are each equal to the number of cards in the chosen player's graveyard.
Whenever the chosen player casts a spell, that player mills a card.

Mistwalker

Changeling (This card is every creature type.)
Flying
{1}{U}: Mistwalker gets +1/-1 until end of turn.

Dreadhound

When Dreadhound enters, mill three cards. (Put the top three cards of your library into your graveyard.)
Whenever a creature dies or a creature card is put into a graveyard from a library, each opponent loses 1 life.

Suspended Sentence

Destroy target creature an opponent controls. That player loses 3 life. Exile Suspended Sentence with three time counters on it.
Suspend 3—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Ravenous Gigamole

When Ravenous Gigamole enters, mill three cards. You may put a creature card from among the cards milled this way into your hand. If you don't, put a +1/+1 counter on Ravenous Gigamole. (To mill a card, put the top card of your library into your graveyard.)

Choked Estuary

As Choked Estuary enters, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters tapped.
{T}: Add {U} or {B}.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Sludge Monster

Whenever Sludge Monster enters or attacks, put a slime counter on up to one other target creature.
Non-Horror creatures with slime counters on them lose all abilities and have base power and toughness 2/2.

Gix's Command

Choose two —
• Put two +1/+1 counters on up to one creature. It gains lifelink until end of turn.
• Destroy each creature with power 2 or less.
• Return up to two creature cards from your graveyard to your hand.
• Each opponent sacrifices a creature with the highest power among creatures they control.

Jace, the Perfected Mind

Compleated ({U/P} can be paid with {U} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
+1: Until your next turn, up to one target creature gets -3/-0.
−2: Target player mills three cards. Then if a graveyard has twenty or more cards in it, you draw three cards. Otherwise, you draw a card.
−X: Target player mills three times X cards.

Mind Flayer

Dominate Monster — When Mind Flayer enters, gain control of target creature for as long as you control Mind Flayer.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Bident of Thassa

Whenever a creature you control deals combat damage to a player, you may draw a card.
{1}{U}, {T}: Creatures your opponents control attack this turn if able.

Maddening Cacophony

Kicker {3}{U}
Each opponent mills eight cards. If this spell was kicked, instead each opponent mills half their library, rounded up.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Maskwood Nexus

Creatures you control are every creature type. The same is true for creature spells you control and creature cards you own that aren't on the battlefield.
{3}, {T}: Create a 2/2 blue Shapeshifter creature token with changeling. (It is every creature type.)

Dreadlight Monstrosity

Ward {2} (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
{3}{U}{U}: Dreadlight Monstrosity can't be blocked this turn. Activate only if you own a card in exile.

Abyssal Gorestalker

When Abyssal Gorestalker enters, each player sacrifices two creatures of their choice.

Murder

Terisian Mindbreaker

Whenever Terisian Mindbreaker attacks, defending player mills half their library, rounded up.
Unearth {1}{U}{U}{U} ({1}{U}{U}{U}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Nemesis of Reason

Whenever Nemesis of Reason attacks, defending player mills ten cards.

Clammy Prowler

Whenever Clammy Prowler attacks, another target attacking creature can't be blocked this turn.

The Mindskinner

The Mindskinner can't be blocked.
If a source you control would deal damage to an opponent, prevent that damage and each opponent mills that many cards.

Forgotten Creation

Skulk (This creature can't be blocked by creatures with greater power.)
At the beginning of your upkeep, you may discard all the cards in your hand. If you do, draw that many cards.

Atris, Oracle of Half-Truths

Menace
When Atris, Oracle of Half-Truths enters, target opponent looks at the top three cards of your library and separates them into a face-down pile and a face-up pile. Put one pile into your hand and the other into your graveyard.

Ravenous Chupacabra

When Ravenous Chupacabra enters, destroy target creature an opponent controls.

Weight of Memory

Draw three cards. Target player mills three cards.

Island

Altar of the Brood

Whenever another permanent you control enters, each opponent mills a card.

Sepulchral Primordial

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
When Sepulchral Primordial enters, for each opponent, you may put up to one target creature card from that player's graveyard onto the battlefield under your control.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Carrion Locust

Flying
When Carrion Locust enters, exile target card from an opponent's graveyard. If it was a creature card, that player loses 1 life.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Darkwater Catacombs

Varragoth, Bloodsky Sire

Deathtouch
Boast — {1}{B}: Target player searches their library for a card, then shuffles and puts that card on top. (Activate only if this creature attacked this turn and only once each turn.)

Chasm Skulker

Whenever you draw a card, put a +1/+1 counter on Chasm Skulker.
When Chasm Skulker dies, create X 1/1 blue Squid creature tokens with islandwalk, where X is the number of +1/+1 counters on Chasm Skulker. (They can't be blocked as long as defending player controls an Island.)

Grazilaxx, Illithid Scholar

Whenever a creature you control becomes blocked, you may return it to its owner's hand.
Whenever one or more creatures you control deal combat damage to a player, draw a card.

Zombify

Return target creature card from your graveyard to the battlefield.

Captain N'ghathrod

Horrors you control have menace.
Whenever a Horror you control deals combat damage to a player, that player mills that many cards.
At the beginning of your end step, choose target artifact or creature card in an opponent's graveyard that was put there from their library this turn. Put it onto the battlefield under your control.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Breach the Multiverse

Each player mills ten cards. For each player, choose a creature or planeswalker card in that player's graveyard. Put those cards onto the battlefield under your control. Then each creature you control becomes a Phyrexian in addition to its other types.

Phyrexian Rager

When Phyrexian Rager enters, you draw a card and you lose 1 life.

Swamp

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Arcane Signet

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Sol Ring

Profane Memento

Whenever a creature card is put into an opponent's graveyard from anywhere, you gain 1 life.

Mind's Dilation

Whenever an opponent casts their first spell each turn, that player exiles the top card of their library. If it's a nonland card, you may cast it without paying its mana cost.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Counterspell

Rise of the Dark Realms

Put all creature cards from all graveyards onto the battlefield under your control.

Thran Dynamo

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Trepanation Blade

Whenever equipped creature attacks, defending player reveals cards from the top of their library until they reveal a land card. The creature gets +1/+0 until end of turn for each card revealed this way. That player puts the revealed cards into their graveyard.
Equip {2}

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Intellect Devourer

Devour Intellect — When Intellect Devourer enters, each opponent exiles a card from their hand until Intellect Devourer leaves the battlefield.
Body Thief — You may play lands and cast spells from among cards exiled with Intellect Devourer. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.