Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Bruvac the Grandiloquent

If an opponent would mill one or more cards, they mill twice that many cards instead. (To mill a card, a player puts the top card of their library into their graveyard.)

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Court of Cunning

When Court of Cunning enters, you become the monarch.
At the beginning of your upkeep, any number of target players each mill two cards. If you're the monarch, each of those players mills ten cards instead. (To mill a card, a player puts the top card of their library into their graveyard.)

Breach the Multiverse

Each player mills ten cards. For each player, choose a creature or planeswalker card in that player's graveyard. Put those cards onto the battlefield under your control. Then each creature you control becomes a Phyrexian in addition to its other types.

Mayhem Devil

Whenever a player sacrifices a permanent, Mayhem Devil deals 1 damage to any target.

Can't Wake Up

Target player mills four cards. (Then exile this card. You may cast the creature later from exile.)

Cruel Somnophage

Cruel Somnophage's power and toughness are each equal to the number of creature cards in all graveyards.

Cruel Somnophage // Can't Wake Up

Chancellor of the Spires

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent mills seven cards.
Flying
When Chancellor of the Spires enters, you may cast target instant or sorcery card from an opponent's graveyard without paying its mana cost.

Blade of Selves

Equipped creature has myriad. (Whenever it attacks, for each opponent other than defending player, you may create a token copy that's tapped and attacking that player or a planeswalker they control. Exile the tokens at end of combat.)
Equip {4}

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Chronic Flooding

Enchant land
Whenever enchanted land becomes tapped, its controller mills three cards.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Infesting Radroach

Flying
Infesting Radroach can't block.
Whenever Infesting Radroach deals combat damage to a player, they get that many rad counters.
Whenever an opponent mills a nonland card, if Infesting Radroach is in your graveyard, you may return it to your hand.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Thraximundar

Haste
Whenever Thraximundar attacks, defending player sacrifices a creature of their choice.
Whenever a player sacrifices a creature, you may put a +1/+1 counter on Thraximundar.

Legate Lanius, Caesar's Ace

Decimate — When Legate Lanius enters, each opponent sacrifices a tenth of the creatures they control of their choice, rounded up.
Whenever an opponent sacrifices a creature, put a +1/+1 counter on Legate Lanius.

Archive Trap

If an opponent searched their library this turn, you may pay {0} rather than pay this spell's mana cost.
Target opponent mills thirteen cards.

Auton Soldier

You may have Auton Soldier enter as a copy of any creature on the battlefield, except it isn't legendary, is an artifact in addition to its other types, and has myriad. (Whenever it attacks, for each opponent other than defending player, you may create a token copy that's tapped and attacking that player or a planeswalker they control. Exile the tokens at end of combat.)

Helm of the Host

At the beginning of combat on your turn, create a token that's a copy of equipped creature, except the token isn't legendary. That token gains haste.
Equip {5}

Lord Xander, the Collector

When Lord Xander, the Collector enters, target opponent discards half the cards in their hand, rounded down.
Whenever Lord Xander attacks, defending player mills half their library, rounded down.
When Lord Xander dies, target opponent sacrifices half the nonland permanents they control of their choice, rounded down.

Altar of the Brood

Whenever another permanent you control enters, each opponent mills a card.

Vengeful Tracker

Whenever an opponent sacrifices an artifact, Vengeful Tracker deals 2 damage to them.

Maddening Cacophony

Kicker {3}{U}
Each opponent mills eight cards. If this spell was kicked, instead each opponent mills half their library, rounded up.