Vizier of Remedies

If one or more -1/-1 counters would be put on a creature you control, that many -1/-1 counters minus one are put on it instead.

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)

Wildgrowth Walker

Whenever a creature you control explores, put a +1/+1 counter on this creature and you gain 3 life.

Bartolomé del Presidio

Sacrifice another creature or artifact: Put a +1/+1 counter on Bartolomé del Presidio.

Safehold Elite

Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)