Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Ambition's Cost

You draw three cards and you lose 3 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Resplendent Angel

Flying
At the beginning of each end step, if you gained 5 or more life this turn, create a 4/4 white Angel creature token with flying and vigilance.
{3}{W}{W}{W}: Until end of turn, Resplendent Angel gets +2/+2 and gains lifelink.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Kabira Crossroads

Kabira Crossroads enters tapped.
When Kabira Crossroads enters, you gain 2 life.
{T}: Add {W}.

Lapse of Certainty

Counter target spell. If that spell is countered this way, put it on top of its owner's library instead of into that player's graveyard.

Thrill of Possibility

As an additional cost to cast this spell, discard a card.
Draw two cards.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Phyrexian Purge

This spell costs 3 life more to cast for each target.
Destroy any number of target creatures.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Mountain

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Lorcan, Warlock Collector

Flying
Whenever a creature card is put into an opponent's graveyard from anywhere, you may pay life equal to its mana value. If you do, put it onto the battlefield under your control. It's a Warlock in addition to its other types.
If a Warlock you control would die, exile it instead.

Nomad Outpost

Nomad Outpost enters tapped.
{T}: Add {R}, {W}, or {B}.

Dark Ritual

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Moltensteel Dragon

({R/P} can be paid with either {R} or 2 life.)
Flying
{R/P}: Moltensteel Dragon gets +1/+0 until end of turn.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Sol Ring

Command Tower

Sign in Blood

Target player draws two cards and loses 2 life.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Red Elemental Blast

Choose one —
• Counter target blue spell.
• Destroy target blue permanent.

Talisman of Conviction

{T}: Add {C}.
{T}: Add {R} or {W}. Talisman of Conviction deals 1 damage to you.

Sunlit Marsh

({T}: Add {W} or {B}.)
Sunlit Marsh enters tapped.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Gift of Estates

If an opponent controls more lands than you, search your library for up to three Plains cards, reveal them, put them into your hand, then shuffle.

Seasoned Cathar

Ambitious Farmhand

When Ambitious Farmhand enters, you may search your library for a basic Plains card, reveal it, put it into your hand, then shuffle.
Coven — {1}{W}{W}: Transform Ambitious Farmhand. Activate only if you control three or more creatures with different powers.

Ambitious Farmhand // Seasoned Cathar

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Licia, Sanguine Tribune

This spell costs {1} less to cast for each 1 life you gained this turn.
First strike, lifelink
Pay 5 life: Put three +1/+1 counters on Licia, Sanguine Tribune. Activate only during your turn and only once each turn.

Wrenn's Resolve

Exile the top two cards of your library. Until the end of your next turn, you may play those cards.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Brotherhood Regalia

Equipped creature has ward {2}, is an Assassin in addition to its other types, and can't be blocked.
Equip legendary creature {1}
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery.)

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Treasonous Ogre

Dethrone (Whenever this creature attacks the player with the most life or tied for most life, put a +1/+1 counter on it.)
Pay 3 life: Add {R}.

Don't Have

Ivory Crane Netsuke

At the beginning of your upkeep, if you have seven or more cards in hand, you gain 4 life.

Spiteflame Witch

Boros Garrison

Boros Garrison enters tapped.
When Boros Garrison enters, return a land you control to its owner's hand.
{T}: Add {R}{W}.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Soul Warden

Whenever another creature enters, you gain 1 life.

Exotic Orchard

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Kayla's Command

Choose two —
• Create a 2/2 colorless Construct artifact creature token.
• Put a +1/+1 counter on a creature you control. It gains double strike until end of turn.
• Search your library for a basic Plains card, reveal it, put it into your hand, then shuffle.
• You gain 2 life and scry 2.

Plains

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Dega Sanctuary

At the beginning of your upkeep, if you control a black or red permanent, you gain 2 life. If you control a black permanent and a red permanent, you gain 4 life instead.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Night's Whisper

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Angel's Feather

Whenever a player casts a white spell, you may gain 1 life.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Xantcha, Sleeper Agent

Xantcha, Sleeper Agent enters under the control of an opponent of your choice.
Xantcha attacks each combat if able and can't attack its owner or planeswalkers its owner controls.
{3}: Xantcha's controller loses 2 life and you draw a card. Any player may activate this ability.

Painful Truths

Converge — You draw X cards and you lose X life, where X is the number of colors of mana spent to cast this spell.

Go for the Throat

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Swamp

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Bedevil

Destroy target artifact, creature, or planeswalker.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Lightning Axe

As an additional cost to cast this spell, discard a card or pay {5}.
Lightning Axe deals 5 damage to target creature.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Rakdos Signet

Worn Powerstone

Worn Powerstone enters tapped.
{T}: Add {C}{C}.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Windborn Muse

Flying
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Firemane Angel

Flying, first strike
At the beginning of your upkeep, if Firemane Angel is in your graveyard or on the battlefield, you may gain 1 life.
{6}{R}{R}{W}{W}: Return Firemane Angel from your graveyard to the battlefield. Activate only during your upkeep.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Congregate

Target player gains 2 life for each creature on the battlefield.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Rakdos Carnarium

Rakdos Carnarium enters tapped.
When Rakdos Carnarium enters, return a land you control to its owner's hand.
{T}: Add {B}{R}.

Greed

Feed the Infection

You draw three cards and you lose 3 life.
Corrupted — Each opponent who has three or more poison counters loses 3 life.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Thriving Moor

Thriving Moor enters tapped. As it enters, choose a color other than black.
{T}: Add {B} or one mana of the chosen color.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Despark

Exile target permanent with mana value 4 or greater.

Pyroblast

Choose one —
• Counter target spell if it's blue.
• Destroy target permanent if it's blue.

Nyx-Fleece Ram

At the beginning of your upkeep, you gain 1 life.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)