Gobhobbler Rats

Hellbent — As long as you have no cards in hand, Gobhobbler Rats gets +1/+0 and has "{B}: Regenerate Gobhobbler Rats." (The next time it would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Demonfire

Demonfire deals X damage to any target. If a creature dealt damage this way would die this turn, exile it instead.
Hellbent — If you have no cards in hand, this spell can't be countered and the damage can't be prevented.

Ghirapur Orrery

Each player may play an additional land on each of their turns.
At the beginning of each player's upkeep, if that player has no cards in hand, that player draws three cards.

Fool's Tome

{2}, {T}: Draw a card. Activate only if you have no cards in hand.

Phoenix Chick

Flying, haste
Phoenix Chick can't block.
Whenever you attack with three or more creatures, you may pay {R}{R}. If you do, return Phoenix Chick from your graveyard to the battlefield tapped and attacking with a +1/+1 counter on it.

Bone Miser

Whenever you discard a creature card, create a 2/2 black Zombie creature token.
Whenever you discard a land card, add {B}{B}.
Whenever you discard a noncreature, nonland card, draw a card.

Blazing Rootwalla

{R}: Blazing Rootwalla gets +2/+0 until end of turn. Activate only once each turn.
Madness {0} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Anje Falkenrath

Haste
{T}, Discard a card: Draw a card.
Whenever you discard a card, if it has madness, untap Anje Falkenrath.

Headless Specter

Flying
Hellbent — Whenever Headless Specter deals combat damage to a player, if you have no cards in hand, that player discards a card at random.

Keldon Megaliths

Keldon Megaliths enters tapped.
{T}: Add {R}.
Hellbent — {1}{R}, {T}: Keldon Megaliths deals 1 damage to any target. Activate only if you have no cards in hand.

Anger

Haste
As long as Anger is in your graveyard and you control a Mountain, creatures you control have haste.

Blood Scrivener

If you would draw a card while you have no cards in hand, instead you draw two cards and you lose 1 life.

Kitchen Imp

Flying, haste
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Anthem of Rakdos

Whenever a creature you control attacks, it gets +2/+0 until end of turn and Anthem of Rakdos deals 1 damage to you.
Hellbent — As long as you have no cards in hand, if a source you control would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Sea Gate Wreckage

{T}: Add {C}. ({C} represents colorless mana.)
{2}{C}, {T}: Draw a card. Activate only if you have no cards in hand.

Nihilistic Glee

{2}{B}, Discard a card: Target opponent loses 1 life and you gain 1 life.
Hellbent — {1}, Pay 2 life: Draw a card. Activate only if you have no cards in hand.

Chainer, Nightmare Adept

Discard a card: You may cast a creature spell from your graveyard this turn. Activate only once each turn.
Whenever a nontoken creature you control enters, if you didn't cast it from your hand, it gains haste until your next turn.

Big Game Hunter

When Big Game Hunter enters, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Cackling Flames

Cackling Flames deals 3 damage to any target.
Hellbent — Cackling Flames deals 5 damage instead if you have no cards in hand.

Terminal Agony

Destroy target creature.
Madness {B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Tragic Fall

Target creature gets -3/-3 until end of turn.
Hellbent — That creature gets -13/-13 until end of turn instead if you have no cards in hand.

Mindstorm Crown

At the beginning of your upkeep, draw a card if you had no cards in hand at the beginning of this turn. If you had a card in hand, Mindstorm Crown deals 1 damage to you.

Glint-Horn Buccaneer

Haste
Whenever you discard a card, Glint-Horn Buccaneer deals 1 damage to each opponent.
{1}{R}, Discard a card: Draw a card. Activate only if Glint-Horn Buccaneer is attacking.

Phial of Galadriel

If you would draw a card while you have no cards in hand, draw two cards instead.
If you would gain life while you have 5 or less life, you gain twice that much life instead.
{T}: Add one mana of any color.

Amber Gristle O'Maul

Haste
Whenever Amber Gristle O'Maul attacks, you may discard your hand. If you do, draw a card for each player being attacked.
Choose a Background (You can have a Background as a second commander.)

Call to the Netherworld

Return target black creature card from your graveyard to your hand.
Madness {0} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Case of the Crimson Pulse

When this Case enters, discard a card, then draw two cards.
To solve — You have no cards in hand. (If unsolved, solve at the beginning of your end step.)
Solved — At the beginning of your upkeep, discard your hand, then draw two cards.

Jagged Poppet

Whenever Jagged Poppet is dealt damage, discard that many cards.
Hellbent — Whenever Jagged Poppet deals combat damage to a player, if you have no cards in hand, that player discards cards equal to the damage.

Anje's Ravager

Anje's Ravager attacks each combat if able.
Whenever Anje's Ravager attacks, discard your hand, then draw three cards.
Madness {1}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Lupine Prototype

Lupine Prototype can't attack or block unless a player has no cards in hand.

Surly Badgersaur

Whenever you discard a creature card, put a +1/+1 counter on Surly Badgersaur.
Whenever you discard a land card, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Whenever you discard a noncreature, nonland card, Surly Badgersaur fights up to one target creature you don't control.

Dark Withering

Destroy target nonblack creature.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Bloodhall Priest

Whenever Bloodhall Priest enters or attacks, if you have no cards in hand, Bloodhall Priest deals 2 damage to any target.
Madness {1}{B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Agent of the Shadow Thieves

Commander creatures you own have "Whenever this creature attacks a player, if no opponent has more life than that player, put a +1/+1 counter on this creature. It gains deathtouch and indestructible until end of turn."