Have

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Demonic Embrace

Enchant creature
Enchanted creature gets +3/+1, has flying, and is a Demon in addition to its other types.
You may cast this card from your graveyard by paying 3 life and discarding a card in addition to paying its other costs.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Replace

Yoshimaru, Ever Faithful

Whenever another legendary permanent you control enters, put a +1/+1 counter on Yoshimaru.
Partner (You can have two commanders if both have partner.)

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Don't Have

Ketramose, the New Dawn

Menace, lifelink, indestructible
Ketramose can't attack or block unless there are seven or more cards in exile.
Whenever one or more cards are put into exile from graveyards and/or the battlefield during your turn, you draw a card and lose 1 life.

Getting

Food

{2}, {T}, Sacrifice this token: You gain 3 life.

Liliana's Contract

When this enchantment enters, you draw four cards and you lose 4 life.
At the beginning of your upkeep, if you control four or more Demons with different names, you win the game.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Shattered Sanctum

This land enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Empyrial Plate

Equipped creature gets +1/+1 for each card in your hand.
Equip {2}

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Reliquary Tower

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Stroke of Midnight

Destroy target nonland permanent. Its controller creates a 1/1 white Human creature token.

Haunted Fengraf

{T}: Add {C}.
{3}, {T}, Sacrifice this land: Return a creature card at random from your graveyard to your hand.

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Abiding Grace

At the beginning of your end step, choose one —
• You gain 1 life.
• Return target creature card with mana value 1 from your graveyard to the battlefield.

Shilgengar, Sire of Famine

Flying
Sacrifice another creature: Create a Blood token. If you sacrificed an Angel this way, create a number of Blood tokens equal to its toughness instead.
{W/B}{W/B}{W/B}, Sacrifice six Blood tokens: Return each creature card from your graveyard to the battlefield with a finality counter on it. Those creatures are Vampires in addition to their other types.

Valgavoth, Terror Eater

Flying, lifelink
Ward—Sacrifice three nonland permanents.
If a card you didn't control would be put into an opponent's graveyard from anywhere, exile it instead.
During your turn, you may play cards exiled with Valgavoth. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Sejiri Glacier

Sejiri Shelter

Target creature you control gains protection from the color of your choice until end of turn.

Sejiri Shelter // Sejiri Glacier

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Ardyn, the Usurper

Demons you control have menace, lifelink, and haste.
Starscourge — At the beginning of combat on your turn, exile up to one target creature card from a graveyard. If you exiled a card this way, create a token that's a copy of that card, except it's a 5/5 black Demon.

Age-Graced Chapel

This land enters tapped.
{T}: Add {W} or {B}.

Glasswing Grace

Enchant creature
Enchanted creature gets +2/+2 and has flying and lifelink.

Glasswing Grace // Age-Graced Chapel

Soltari Visionary

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever this creature deals damage to a player, destroy target enchantment that player controls.

Dream Devourer

Each nonland card in your hand without foretell has foretell. Its foretell cost is equal to its mana cost reduced by {2}. (During your turn, you may pay {2} and exile it from your hand face down. Cast it on a later turn for its foretell cost.)
Whenever you foretell a card, this creature gets +2/+0 until end of turn.

Sol Ring

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, this creature gets +5/+5 and has flying.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It is every creature type.)

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Harvester of Souls

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever another nontoken creature dies, you may draw a card.

Parting Thoughts

Destroy target creature. You draw X cards and you lose X life, where X is the number of counters on that creature.

Mortuary Mire

This land enters tapped.
When this land enters, you may put target creature card from your graveyard on top of your library.
{T}: Add {B}.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. This land deals 1 damage to you.

Kagemaro, First to Suffer

Kagemaro's power and toughness are each equal to the number of cards in your hand.
{B}, Sacrifice Kagemaro: All creatures get -X/-X until end of turn, where X is the number of cards in your hand.

Dark Ritual

Empyrial Armor

Enchant creature
Enchanted creature gets +1/+1 for each card in your hand.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. This artifact deals 1 damage to you.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Mantle of the Ancients

Enchant creature you control
When this Aura enters, return any number of target Aura and/or Equipment cards from your graveyard to the battlefield attached to enchanted creature.
Enchanted creature gets +1/+1 for each Aura and Equipment attached to it.

Blade of the Oni

Menace
Equipped creature has base power and toughness 5/5, has menace, and is a black Demon in addition to its other colors and types.
Reconfigure {2}{B}{B} ({2}{B}{B}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Desolate Mire

Changeling Outcast

Changeling (This card is every creature type.)
This creature can't block and can't be blocked.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Withengar Unbound

Flying, intimidate, trample (A creature with intimidate can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever a player loses the game, put thirteen +1/+1 counters on Withengar Unbound.

Elbrus, the Binding Blade

Equipped creature gets +1/+0.
When equipped creature deals combat damage to a player, unattach Elbrus, then transform it.
Equip {1}

Elbrus, the Binding Blade // Withengar Unbound

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Human Cleric

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Ormendahl, Profane Prince

Westvale Abbey

{T}: Add {C}.
{5}, {T}, Pay 1 life: Create a 1/1 white and black Human Cleric creature token.
{5}, {T}, Sacrifice five creatures: Transform this land, then untap it.

Westvale Abbey // Ormendahl, Profane Prince

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Hand of Vecna

At the beginning of combat on your turn, equipped creature or a creature you control named Vecna gets +X/+X until end of turn, where X is the number of cards in your hand.
Equip—Pay 1 life for each card in your hand.
Equip {2}

Wrath of God

Destroy all creatures. They can't be regenerated.

Mangara, the Diplomat

Lifelink
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, draw a card.
Whenever an opponent casts their second spell each turn, draw a card.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Qarsi Revenant

Flying, deathtouch, lifelink
Renew — {2}{B}, Exile this card from your graveyard: Put a flying counter, a deathtouch counter, and a lifelink counter on target creature. Activate only as a sorcery.

Vault of Champions

This land enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Vecna

Selfless Spirit

Flying
Sacrifice this creature: Creatures you control gain indestructible until end of turn.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Blood

{1}, {T}, Discard a card, Sacrifice this token: Draw a card.

Restless Fortress

This land enters tapped.
{T}: Add {W} or {B}.
{2}{W}{B}: This land becomes a 1/4 white and black Nightmare creature until end of turn. It's still a land.
Whenever this land attacks, defending player loses 2 life and you gain 2 life.

Culling the Weak

As an additional cost to cast this spell, sacrifice a creature.
Add {B}{B}{B}{B}.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Human

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice this creature: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice this land: Draw a card.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Isolated Chapel

This land enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Silence

Your opponents can't cast spells this turn.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Baldin, Century Herdmaster

During your turn, each creature assigns combat damage equal to its toughness rather than its power.
Whenever Baldin attacks, up to one hundred target creatures each get +0/+X until end of turn, where X is the number of cards in your hand.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Phyrexian Germ

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Plains

Swamp

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Shadowgrange Archfiend

When this creature enters, each opponent sacrifices a creature with the greatest power among creatures they control. You gain life equal to the greatest power among creatures sacrificed this way.
Madness—{2}{B}, Pay 8 life. (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Vault of the Archangel

{T}: Add {C}.
{2}{W}{B}, {T}: Creatures you control gain deathtouch and lifelink until end of turn.