Disdainful Stroke

Counter target spell with mana value 4 or greater.

Reject Imperfection

Counter target spell. If that spell's mana value was 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Deadly Cover-Up

As an additional cost to cast this spell, you may collect evidence 6.
Destroy all creatures. If evidence was collected, exile a card from an opponent's graveyard. Then search its owner's graveyard, hand, and library for any number of cards with that name and exile them. That player shuffles, then draws a card for each card exiled from their hand this way.

Rotten Reunion

Exile up to one target card from a graveyard. Create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)
Flashback {1}{B} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Pithing Needle

As Pithing Needle enters, choose a card name.
Activated abilities of sources with the chosen name can't be activated unless they're mana abilities.

Bring the Ending

Counter target spell unless its controller pays {2}.
Corrupted — Counter that spell instead if its controller has three or more poison counters.

Island

Spell Pierce

Counter target noncreature spell unless its controller pays {2}.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Negate

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Dismal Backwater

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {U} or {B}.

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Swamp

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

Distorted Curiosity

Corrupted — This spell costs {2} less to cast if an opponent has three or more poison counters.
Draw two cards.