Megrim

Whenever an opponent discards a card, this enchantment deals 2 damage to that player.

Paupers' Cage

At the beginning of each opponent's upkeep, if that player has two or fewer cards in hand, this artifact deals 2 damage to that player.

Liliana of the Veil

+1: Each player discards a card.
−2: Target player sacrifices a creature.
−6: Separate all permanents target player controls into two piles. That player sacrifices all permanents in the pile of their choice.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Rackling

At the beginning of each opponent's upkeep, this creature deals X damage to that player, where X is 3 minus the number of cards in their hand.

Ensnaring Bridge

Creatures with power greater than the number of cards in your hand can't attack.

Miasmic Mummy

When this creature enters, each player discards a card.

Dark Ritual

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Tasigur's Cruelty

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Each opponent discards two cards.

Wheel of Torture

At the beginning of each opponent's upkeep, this artifact deals X damage to that player, where X is 3 minus the number of cards in their hand.

The Rack

As this artifact enters, choose an opponent.
At the beginning of the chosen player's upkeep, this artifact deals X damage to that player, where X is 3 minus the number of cards in their hand.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel deals 2 damage to them.
−1: Target player discards a card.

Liliana's Specter

Flying
When this creature enters, each opponent discards a card.

Burglar Rat

When this creature enters, each opponent discards a card.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Rotting Rats

When this creature enters, each player discards a card.
Unearth {1}{B} ({1}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Hymn to Tourach

Target player discards two cards at random.

Faith of the Devoted

Whenever you cycle or discard a card, you may pay {1}. If you do, each opponent loses 2 life and you gain 2 life.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Mindslicer

When this creature dies, each player discards their hand.

Mind Twist

Target player discards X cards at random.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Damnation

Destroy all creatures. They can't be regenerated.

Hypnotic Specter

Flying
Whenever this creature deals damage to an opponent, that player discards a card at random.

Liliana's Triumph

Each opponent sacrifices a creature of their choice. If you control a Liliana planeswalker, each opponent also discards a card.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Swamp

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Skullcage

At the beginning of each opponent's upkeep, this artifact deals 2 damage to that player unless they have exactly three or exactly four cards in hand.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on this enchantment.
At the beginning of each opponent's upkeep, if that player has no cards in hand and this enchantment has two or more quest counters on it, you may have that player lose 5 life.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Liliana, Defiant Necromancer

+2: Each player discards a card.
−X: Return target nonlegendary creature card with mana value X from your graveyard to the battlefield.
−8: You get an emblem with "Whenever a creature dies, return it to the battlefield under your control at the beginning of the next end step."

Liliana, Heretical Healer

Lifelink
Whenever another nontoken creature you control dies, exile Liliana, Heretical Healer, then return her to the battlefield transformed under her owner's control. If you do, create a 2/2 black Zombie creature token.

Liliana, Heretical Healer // Liliana, Defiant Necromancer

Abyssal Gatekeeper

When this creature dies, each player sacrifices a creature of their choice.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip this creature.

Nezumi Shortfang // Stabwhisker the Odious

Plaguecrafter

When this creature enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Vona's Hunger

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
Each opponent sacrifices a creature of their choice. If you have the city's blessing, instead each opponent sacrifices half the creatures they control of their choice, rounded up.