Tower Defense

Creatures you control get +0/+5 and gain reach until end of turn.

The Pride of Hull Clade

This spell costs {X} less to cast, where X is the total toughness of creatures you control.
Defender
{2}{U}{U}: Until end of turn, target creature you control gets +1/+0, gains "Whenever this creature deals combat damage to a player, draw cards equal to its toughness," and can attack as though it didn't have defender.

Jeskai Barricade

Flash (You may cast this spell any time you could cast an instant.)
Defender
When Jeskai Barricade enters, you may return another target creature you control to its owner's hand.

Huatli, the Sun's Heart

Each creature you control assigns combat damage equal to its toughness rather than its power.
−3: You gain life equal to the greatest toughness among creatures you control.

Iymrith, Desert Doom

Flying
Iymrith, Desert Doom has ward {4} as long as it's untapped.
Whenever Iymrith deals combat damage to a player, draw a card. Then if you have fewer than three cards in hand, draw cards equal to the difference.

Vault 75: Middle School

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Exile all creatures with power 4 or greater.
II, III — Put a +1/+1 counter on each creature you control.

Stalwart Shield-Bearers

Defender
Other creatures you control with defender get +0/+2.

Teyo, the Shieldmage

You have hexproof. (You can't be the target of spells or abilities your opponents control.)
−2: Create a 0/3 white Wall creature token with defender.

Fortified Rampart

Teyo, Geometric Tactician

When Teyo, Geometric Tactician enters, create a 0/4 white Wall creature token with defender and flying.
+1: You and target opponent each draw a card.
−2: Choose left or right. Until your next turn, each player may attack only the nearest opponent in the last chosen direction and planeswalkers controlled by that opponent.

Sanctuary Wall

Defender
{2}{W}, {T}: Tap target creature. You may put a stun counter on it. If you do, put a stun counter on Sanctuary Wall. (If a permanent with a stun counter would become untapped, remove one from it instead.)

Wall of Denial

Defender, flying
Shroud (This creature can't be the target of spells or abilities.)

High Alert

Each creature you control assigns combat damage equal to its toughness rather than its power.
Creatures you control can attack as though they didn't have defender.
{2}{W}{U}: Untap target creature.

Axebane Guardian

Defender
{T}: Add X mana in any combination of colors, where X is the number of creatures you control with defender.

Arcades, the Strategist

Flying, vigilance
Whenever a creature you control with defender enters, draw a card.
Each creature you control with defender assigns combat damage equal to its toughness rather than its power and can attack as though it didn't have defender.

Wall of Runes

Defender (This creature can't attack.)
When Wall of Runes enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Triskaidekaphile

You have no maximum hand size.
At the beginning of your upkeep, if you have exactly thirteen cards in your hand, you win the game.
{3}{U}: Draw a card.