Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Flesh Reaver

Whenever Flesh Reaver deals damage to a creature or opponent, Flesh Reaver deals that much damage to you.

Counterspell

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Archfiend of the Dross

Flying
Archfiend of the Dross enters with four oil counters on it.
At the beginning of your upkeep, remove an oil counter from Archfiend of the Dross. Then if it has no oil counters on it, you lose the game.
Whenever a creature an opponent controls dies, its controller loses 2 life.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.

Plague Reaver

At the beginning of your end step, sacrifice each other creature you control.
Discard two cards, Sacrifice Plague Reaver: Choose target opponent. Return Plague Reaver to the battlefield under that player's control at the beginning of their next upkeep.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Sol Ring

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Necrogen Communion

Enchant creature you control
Enchanted creature has toxic 2. (Players dealt combat damage by it also get two poison counters.)
When enchanted creature dies, return that card to the battlefield under your control.

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control of their choice, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Island

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Reins of Power

Untap all creatures you control and all creatures target opponent controls. You and that opponent each gain control of all creatures the other controls until end of turn. Those creatures gain haste until end of turn.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sly Instigator

{U}, {T}: Until your next turn, target creature an opponent controls can't be blocked. Goad that creature. (Until your next turn, that creature attacks each combat if able and attacks a player other than you if able.)

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker of their choice.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Reject Imperfection

Counter target spell. If that spell's mana value was 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tablet of Compleation

{T}: Put an oil counter on Tablet of Compleation.
{T}: Add {C}. Activate only if Tablet of Compleation has two or more oil counters on it.
{1}, {T}: Draw a card. Activate only if Tablet of Compleation has five or more oil counters on it.

Dimir Signet

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Bilious Skulldweller

Deathtouch
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

The True Scriptures

(As this Saga enters and after your draw step, add a lore counter.)
I — For each opponent, destroy up to one target creature or planeswalker that player controls.
II — Each opponent discards three cards, then mills three cards.
III — Put all creature cards from all graveyards onto the battlefield under your control. Exile The True Scriptures, then return it to the battlefield (front face up).

Sheoldred

Menace
When Sheoldred enters, each opponent sacrifices a nontoken creature or planeswalker of their choice.
{4}{B}: Exile Sheoldred, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if an opponent has eight or more cards in their graveyard.

Sheoldred // The True Scriptures

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyrexian Soulgorger

Cumulative upkeep—Sacrifice a creature. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Phyrexian Negator

Trample
Whenever Phyrexian Negator is dealt damage, sacrifice that many permanents.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Bring the Ending

Counter target spell unless its controller pays {2}.
Corrupted — Counter that spell instead if its controller has three or more poison counters.

Sunken Ruins

{T}: Add {C}.
{U/B}, {T}: Add {U}{U}, {U}{B}, or {B}{B}.

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Feed the Infection

You draw three cards and you lose 3 life.
Corrupted — Each opponent who has three or more poison counters loses 3 life.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Offer Immortality

Target creature gains deathtouch and indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Dissipation Field

Whenever a permanent deals damage to you, return it to its owner's hand.

Vat of Rebirth

Whenever another artifact or creature you control is put into a graveyard from the battlefield, put an oil counter on Vat of Rebirth.
{2}{B}, {T}, Remove four oil counters from Vat of Rebirth: Return target creature card from your graveyard to the battlefield. Activate only as a sorcery.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

The Great Synthesis

(As this Saga enters and after your draw step, add a lore counter.)
I — Draw cards equal to the number of cards in your hand. You have no maximum hand size for as long as you control The Great Synthesis.
II — Return all non-Phyrexian creatures to their owners' hands.
III — You may cast any number of spells from your hand without paying their mana costs. Exile The Great Synthesis, then return it to the battlefield (front face up).

Jin-Gitaxias

Ward {2}
Whenever you cast a noncreature spell with mana value 3 or greater, draw a card.
{3}{U}: Exile Jin-Gitaxias, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if you have seven or more cards in hand.

Jin-Gitaxias // The Great Synthesis

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Darkwater Catacombs

Rotting Regisaur

At the beginning of your upkeep, discard a card.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tainted Isle

{T}: Add {C}.
{T}: Add {U} or {B}. Activate only if you control a Swamp.

Swamp

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Modify Memory

Exchange control of two target creatures controlled by different players. If you control neither creature, draw three cards.

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Realmbreaker, the Invasion Tree

{2}, {T}: Target opponent mills three cards. Put a land card from their graveyard onto the battlefield tapped under your control. It gains "If this land would leave the battlefield, exile it instead of putting it anywhere else."
{10}, {T}, Sacrifice Realmbreaker, the Invasion Tree: Search your library for any number of Praetor cards, put them onto the battlefield, then shuffle.

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Dark Ritual

Three Steps Ahead

Spree (Choose one or more additional costs.)
+ {1}{U} — Counter target spell.
+ {3} — Create a token that's a copy of target artifact or creature you control.
+ {2} — Draw two cards, then discard a card.

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Arcane Signet

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Blue Sun's Twilight

Gain control of target creature with mana value X or less. If X is 5 or more, create a token that's a copy of that creature.

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Venser, Corpse Puppet

Lifelink, toxic 1
Whenever you proliferate, choose one —
• If you don't control a creature named The Hollow Sentinel, create The Hollow Sentinel, a legendary 3/3 colorless Phyrexian Golem artifact creature token.
• Target artifact creature you control gains flying and lifelink until end of turn.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Curse of Verbosity

Enchant player
Whenever enchanted player is attacked, you draw a card. Each opponent attacking that player does the same.

Curse of the Swine

Exile X target creatures. For each creature exiled this way, its controller creates a 2/2 green Boar creature token.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.