Wave of Vitriol

Each player sacrifices all artifacts, enchantments, and nonbasic lands they control. For each land sacrificed this way, its controller may search their library for a basic land card and put it onto the battlefield tapped. Then each player who searched their library this way shuffles.

Final Act

Choose one or more —
• Destroy all creatures.
• Destroy all planeswalkers.
• Destroy all battles.
• Exile all graveyards.
• Each opponent loses all counters.

Path of Peril

Cleave {4}{W}{B} (You may cast this spell for its cleave cost. If you do, remove the words in square brackets.)
Destroy all creatures [with mana value 2 or less].

Worldslayer

Whenever equipped creature deals combat damage to a player, destroy all permanents other than this Equipment.
Equip {5} ({5}: Attach to target creature you control. Equip only as a sorcery.)

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Sandswirl Wanderglyph

Flying
Whenever an opponent casts a spell during their turn, they can't attack you or planeswalkers you control this turn.
Each opponent who attacked you or a planeswalker you control this turn can't cast spells.

Unstable Glyphbridge

When this artifact enters, if you cast it, for each player, choose a creature with power 2 or less that player controls. Then destroy all creatures except creatures chosen this way.
Craft with artifact {3}{W}{W} ({3}{W}{W}, Exile this artifact, Exile another artifact you control or an artifact card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Unstable Glyphbridge // Sandswirl Wanderglyph

The Battle of Bywater

Destroy all creatures with power 3 or greater. Then create a Food token for each creature you control. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Rout

You may cast this spell as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

March of Souls

Destroy all creatures. They can't be regenerated. For each creature destroyed this way, its controller creates a 1/1 white Spirit creature token with flying.

Fortunate Few

Choose a nonland permanent you don't control, then each other player chooses a nonland permanent they don't control that hasn't been chosen this way. Destroy all other nonland permanents.

Magus of the Disk

This creature enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Spectacular Pileup

All creatures and Vehicles lose indestructible until end of turn, then destroy all creatures and Vehicles.
Cycling {2} ({2}, Discard this card: Draw a card.)

Obliterate

This spell can't be countered.
Destroy all artifacts, creatures, and lands. They can't be regenerated.

Structural Assault

Destroy all artifacts, then Structural Assault deals damage to each creature equal to the number of artifacts that were put into graveyards from the battlefield this turn.

Oversimplify

Exile all creatures. Each player creates a 0/0 green and blue Fractal creature token and puts a number of +1/+1 counters on it equal to the total power of creatures they controlled that were exiled this way.

Exterminatus

Nonland permanents your opponents control lose indestructible until end of turn.
Destroy all nonland permanents.

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Ritual of Soot

Destroy all creatures with mana value 3 or less.

Explosive Getaway

Exile up to one target artifact or creature. Return it to the battlefield under its owner's control at the beginning of the next end step.
Explosive Getaway deals 4 damage to each creature.

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

One Ring to Rule Them All

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — The Ring tempts you, then each player mills cards equal to your Ring-bearer's power.
II — Destroy all nonlegendary creatures.
III — Each opponent loses 1 life for each creature card in that player's graveyard.

Blood Money

Destroy all creatures. For each nontoken creature destroyed this way, you create a tapped Treasure token.

The Night of the Doctor

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after II.)
I — Destroy all creatures.
II — Return target legendary creature card from your graveyard to the battlefield. Put your choice of a first strike, vigilance, or lifelink counter on it.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Life's Finale

Destroy all creatures, then search target opponent's library for up to three creature cards and put them into their graveyard. Then that player shuffles.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Devastating Mastery

You may pay {2}{W}{W} rather than pay this spell's mana cost.
If the {2}{W}{W} cost was paid, an opponent chooses up to two nonland permanents they control and returns them to their owner's hand.
Destroy all nonland permanents.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Pest Control

Destroy all nonland permanents with mana value 1 or less.
Cycling {2} ({2}, Discard this card: Draw a card.)

Guan Yu's 1,000-Li March

Necromantic Selection

Destroy all creatures, then return a creature card put into a graveyard this way to the battlefield under your control. It's a black Zombie in addition to its other colors and types. Exile Necromantic Selection.

Wrath of God

Destroy all creatures. They can't be regenerated.

Dimensional Breach

Exile all permanents. For as long as any of those cards remain exiled, at the beginning of each player's upkeep, that player returns one of the exiled cards they own to the battlefield.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Crisis of Conscience

Choose one —
• Destroy all tokens.
• Destroy all nonland, nontoken permanents.

Sunscour

You may exile two white cards from your hand rather than pay this spell's mana cost.
Destroy all creatures.

Damnation

Marchesa, Resolute Monarch

Menace, deathtouch
Whenever Marchesa attacks, remove all counters from up to one target permanent.
At the beginning of your upkeep, if you haven't been dealt combat damage since your last turn, you draw a card and you lose 1 life.

Invasion of Fiora

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When this Siege enters, choose one or both —
• Destroy all legendary creatures.
• Destroy all nonlegendary creatures.

Invasion of Fiora // Marchesa, Resolute Monarch

Phyrexian Scriptures

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Put a +1/+1 counter on up to one target creature. That creature becomes an artifact in addition to its other types.
II — Destroy all nonartifact creatures.
III — Exile all opponents' graveyards.

Kirtar's Wrath

Destroy all creatures. They can't be regenerated.
Threshold — If seven or more cards are in your graveyard, instead destroy all creatures, then create two 1/1 white Spirit creature tokens with flying. Creatures destroyed this way can't be regenerated.

Angel of the Dire Hour

Flash
Flying
When this creature enters, if you cast it from your hand, exile all attacking creatures.

The Filigree Sylex

{T}: Put an oil counter on The Filigree Sylex.
{T}, Sacrifice The Filigree Sylex: Destroy each nonland permanent with mana value equal to the number of oil counters on The Filigree Sylex.
{T}, Remove ten oil counters from among permanents you control and sacrifice The Filigree Sylex: It deals 10 damage to any target.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Worldfire

Exile all permanents. Exile all cards from all hands and graveyards. Each player's life total becomes 1.

Starfall Invocation

Gift a card (You may promise an opponent a gift as you cast this spell. If you do, they draw a card before its other effects.)
Destroy all creatures. If the gift was promised, return a creature card put into your graveyard this way to the battlefield under your control.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Sunfall

Exile all creatures. Incubate X, where X is the number of creatures exiled this way. (Create an Incubator token with X +1/+1 counters on it and "{2}: Transform this token." It transforms into a 0/0 Phyrexian artifact creature.)

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle this card, all creatures get -2/-2 until end of turn.

Ondu Skyruins

Ondu Inversion

Ondu Inversion // Ondu Skyruins

Soulscour

Final Judgment

Vault 75: Middle School

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Exile all creatures with power 4 or greater.
II, III — Put a +1/+1 counter on each creature you control.

Plague Wind

Destroy all creatures you don't control. They can't be regenerated.

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Damning Verdict

Destroy all creatures with no counters on them.

Slash the Ranks

Destroy all creatures and planeswalkers except for commanders.

Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Descend upon the Sinful

Exile all creatures.
Delirium — Create a 4/4 white Angel creature token with flying if there are four or more card types among cards in your graveyard.

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Expel the Interlopers

Choose a number between 0 and 10. Destroy all creatures with power greater than or equal to the chosen number.

Aether Snap

Remove all counters from all permanents and exile all tokens.

Blasphemous Edict

You may pay {B} rather than pay this spell's mana cost if there are thirteen or more creatures on the battlefield.
Each player sacrifices thirteen creatures of their choice.

Extinguish All Hope

Citywide Bust

Destroy all creatures with toughness 4 or greater.

Urza's Ruinous Blast

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Exile all nonland permanents that aren't legendary.

The Nipton Lottery

Choose a creature at random. You gain control of that creature until end of turn. Untap it. It gains haste until end of turn. Then destroy all other creatures.

Planar Outburst

Destroy all nonland creatures.
Awaken 4—{5}{W}{W}{W} (If you cast this spell for {5}{W}{W}{W}, also put four +1/+1 counters on target land you control and it becomes a 0/0 Elemental creature with haste. It's still a land.)

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Solar Tide

Choose one —
• Destroy all creatures with power 2 or less.
• Destroy all creatures with power 3 or greater.
Entwine—Sacrifice two lands. (Choose both if you pay the entwine cost.)

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Mass Calcify

Bontu's Last Reckoning

Destroy all creatures. Lands you control don't untap during your next untap step.

Deathbringer Regent

Flying
When this creature enters, if you cast it from your hand and there are five or more other creatures on the battlefield, destroy all other creatures.

Mandate of Abaddon

Choose target creature you control. Destroy all creatures with power less than that creature's power.

Mageta the Lion

{2}{W}{W}, {T}, Discard two cards: Destroy all creatures except for Mageta. Those creatures can't be regenerated.

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Shadows' Verdict

Exile all creatures and planeswalkers with mana value 3 or less from the battlefield and all creature and planeswalker cards with mana value 3 or less from all graveyards.

Day of Judgment

Urza's Sylex

{2}{W}{W}, {T}, Exile Urza's Sylex: Each player chooses six lands they control. Destroy all other permanents. Activate only as a sorcery.
When Urza's Sylex is put into exile from the battlefield, you may pay {2}. If you do, search your library for a planeswalker card, reveal it, put it into your hand, then shuffle.

Boompile

{T}: Flip a coin. If you win the flip, destroy all nonland permanents.

Don't Move

Destroy all tapped creatures. Until your next turn, whenever a creature becomes tapped, destroy it.

Sunblast Angel

Flying
When this creature enters, destroy all tapped creatures.

Fell the Mighty

Destroy all creatures with power greater than target creature's power.

Novablast Wurm

Whenever this creature attacks, destroy all other creatures.

Retribution of the Meek

Destroy all creatures with power 4 or greater. They can't be regenerated.

Play of the Game

Assist (Another player can pay up to {6} of this spell's cost.)
Exile all nonland permanents.

Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

White Sun's Twilight

You gain X life. Create X 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This token can't block." If X is 5 or more, destroy all other creatures. (Players dealt combat damage by a creature with toxic 1 also get a poison counter.)

Planar Cleansing

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Nevinyrral's Disk

This artifact enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Martial Coup

Create X 1/1 white Soldier creature tokens. If X is 5 or more, destroy all other creatures.

Final Showdown

Spree (Choose one or more additional costs.)
+ {1} — All creatures lose all abilities until end of turn.
+ {1} — Choose a creature you control. It gains indestructible until end of turn.
+ {3}{W}{W} — Destroy all creatures.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Nevinyrral, Urborg Tyrant

Hexproof from artifacts, creatures, and enchantments
When Nevinyrral enters, create a tapped 2/2 black Zombie creature token for each creature that died this turn.
When Nevinyrral dies, you may pay {1}. When you do, destroy all artifacts, creatures, and enchantments.