Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature of their choice and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Faith's Fetters

Enchant permanent
When Faith's Fetters enters, you gain 4 life.
Enchanted permanent can't attack or block, and its activated abilities can't be activated unless they're mana abilities.

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker of their choice.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Armor of Shadows

Until end of turn, target creature gets +1/+0 and gains indestructible. (Damage and effects that say "destroy" don't destroy it.)

Recumbent Bliss

Enchant creature
Enchanted creature can't attack or block.
At the beginning of your upkeep, you may gain 1 life.

Rupture Spire

Rupture Spire enters tapped.
When Rupture Spire enters, sacrifice it unless you pay {1}.
{T}: Add one mana of any color.

Knight of Obligation

Vigilance
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Heliod's Pilgrim

When Heliod's Pilgrim enters, you may search your library for an Aura card, reveal it, put it into your hand, then shuffle.

Serrated Scorpion

When Serrated Scorpion dies, it deals 2 damage to each opponent and you gain 2 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Malakir Familiar

Flying, deathtouch
Whenever you gain life, Malakir Familiar gets +1/+1 until end of turn.

Morgul-Knife Wound

Enchant creature
Enchanted creature gets -3/-0 and has "At the beginning of your upkeep, exile this creature unless you pay 2 life."

Bone Picker

This spell costs {3} less to cast if a creature died this turn.
Flying, deathtouch

Teysa, Envoy of Ghosts

Vigilance, protection from creatures
Whenever a creature deals combat damage to you, destroy that creature. Create a 1/1 white and black Spirit creature token with flying.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Idyllic Beachfront

({T}: Add {W} or {U}.)
Idyllic Beachfront enters tapped.

Neva, Stalked by Nightmares

Menace
When Neva, Stalked by Nightmares enters, return target creature or enchantment card from your graveyard to your hand.
Whenever an enchantment you control is put into a graveyard from the battlefield, put a +1/+1 counter on Neva, then scry 1.

Snow-Covered Swamp

Firja's Retribution

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Create a 4/4 white Angel Warrior creature token with flying and vigilance.
II — Until end of turn, Angels you control gain "{T}: Destroy target creature with power less than this creature's power."
III — Angels you control gain double strike until end of turn.

Arcane Sanctum

Arcane Sanctum enters tapped.
{T}: Add {W}, {U}, or {B}.

Gift of Orzhova

Enchant creature
Enchanted creature gets +1/+1 and has flying and lifelink.

Gateway Plaza

Gateway Plaza enters tapped.
When Gateway Plaza enters, sacrifice it unless you pay {1}.
{T}: Add one mana of any color.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Don't Have

Absorb

Last Thoughts

Draw a card.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Plains

Dismal Backwater

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {U} or {B}.

Regal Bloodlord

Flying
At the beginning of each end step, if you gained life this turn, create a 1/1 black Bat creature token with flying.

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Quench

Counter target spell unless its controller pays {2}.

Invocation of Saint Traft

Enchant creature
Enchanted creature has "Whenever this creature attacks, create a 4/4 white Angel creature token with flying that's tapped and attacking. Exile that token at end of combat."

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Skybridge Towers

Skybridge Towers enters tapped.
{T}: Add {W} or {U}.
{2}{W}{U}, {T}, Sacrifice Skybridge Towers: Draw a card.

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
This creature gets +2/+2 as long as you have 25 or more life.

MacCready, Lamplight Mayor

Whenever a creature you control with power 2 or less attacks, it gains skulk until end of turn. (It can't be blocked by creatures with greater power.)
Whenever a creature with power 4 or greater attacks you, its controller loses 2 life and you gain 2 life.

Modify Memory

Exchange control of two target creatures controlled by different players. If you control neither creature, draw three cards.

Paladin of Atonement

At the beginning of each upkeep, if you lost life last turn, put a +1/+1 counter on Paladin of Atonement.
When Paladin of Atonement dies, you gain life equal to its toughness.

Relic Bane

Enchant artifact
Enchanted artifact has "At the beginning of your upkeep, you lose 2 life."

Temple of Silence

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {B}.

Famished Paladin

Famished Paladin doesn't untap during your untap step.
Whenever you gain life, untap Famished Paladin.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Hired Poisoner

Ajani, Strength of the Pride

+1: You gain life equal to the number of creatures you control plus the number of planeswalkers you control.
−2: Create a 2/2 white Cat Soldier creature token named Ajani's Pridemate with "Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate."
0: If you have at least 15 life more than your starting life total, exile Ajani, Strength of the Pride and each artifact and creature your opponents control.

Island

Blighted Fen

{T}: Add {C}.
{4}{B}, {T}, Sacrifice Blighted Fen: Target opponent sacrifices a creature of their choice.

Rune-Tail's Essence

Prevent all damage that would be dealt to creatures you control.

Rune-Tail, Kitsune Ascendant

When you have 30 or more life, flip Rune-Tail, Kitsune Ascendant.

Rune-Tail, Kitsune Ascendant // Rune-Tail's Essence

Village Bell-Ringer

Flash (You may cast this spell any time you could cast an instant.)
When Village Bell-Ringer enters, untap all creatures you control.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Orzhov Charm

Choose one —
• Return target creature you control and all Auras you control attached to it to their owner's hand.
• Destroy target creature and you lose life equal to its toughness.
• Return target creature card with mana value 1 or less from your graveyard to the battlefield.

Ajani, Inspiring Leader

+2: You gain 2 life. Put two +1/+1 counters on up to one target creature.
−3: Exile target creature. Its controller gains 2 life.
−10: Creatures you control gain flying and double strike until end of turn.

Negate

Lobelia Sackville-Baggins

Flash
Menace
When Lobelia Sackville-Baggins enters, exile target creature card from an opponent's graveyard that was put there from the battlefield this turn, then create X Treasure tokens, where X is the exiled card's power.

Kalastria Nightwatch

Whenever you gain life, Kalastria Nightwatch gains flying until end of turn.

Contaminated Ground

Enchant land
Enchanted land is a Swamp.
Whenever enchanted land becomes tapped, its controller loses 2 life.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Cleric of Life's Bond

Whenever another Cleric you control enters, you gain 1 life.
Whenever you gain life for the first time each turn, put a +1/+1 counter on Cleric of Life's Bond.

Pacifism

Enchant creature
Enchanted creature can't attack or block.

Call of the Nightwing

Create a 1/1 blue and black Horror creature token with flying.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Doomskar Oracle

Whenever you cast your second spell each turn, you gain 2 life.
Foretell {W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Ministrant of Obligation

Afterlife 2 (When this creature dies, create two 1/1 white and black Spirit creature tokens with flying.)

Daxos, Blessed by the Sun

Daxos's toughness is equal to your devotion to white. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Whenever another creature you control enters or dies, you gain 1 life.

Paladin of the Bloodstained

When Paladin of the Bloodstained enters, create a 1/1 white Vampire creature token with lifelink.

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Demonic Vigor

Enchant creature
Enchanted creature gets +1/+1.
When enchanted creature dies, return that card to its owner's hand.

Tranquil Cove

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {W} or {U}.

Scoured Barrens

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {W} or {B}.

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Sanguine Savior

Flying, lifelink
Disguise {W/B}{W/B} (You may cast this card face down for {3} as a 2/2 creature with ward {2}. Turn it face up any time for its disguise cost.)
When Sanguine Savior is turned face up, another target creature you control gains lifelink until end of turn.

Imperious Oligarch

Vigilance
Afterlife 1 (When this creature dies, create a 1/1 white and black Spirit creature token with flying.)

Final Payment

As an additional cost to cast this spell, pay 5 life or sacrifice a creature or enchantment.
Destroy target creature.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Essence Scatter

Nyx-Fleece Ram

At the beginning of your upkeep, you gain 1 life.

Vengeful Reaper

Flying, deathtouch, haste
Foretell {1}{B} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Mortify

Mark of the Vampire

Enchant creature
Enchanted creature gets +2/+2 and has lifelink.

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.

Eel Umbra

Flash (You may cast this spell any time you could cast an instant.)
Enchant creature
Enchanted creature gets +1/+1.
Umbra armor (If enchanted creature would be destroyed, instead remove all damage from it and destroy this Aura.)

Dark Prophecy

Whenever a creature you control dies, you draw a card and you lose 1 life.

Gollum, Obsessed Stalker

Skulk (This creature can't be blocked by creatures with greater power.)
At the beginning of your end step, each opponent dealt combat damage this game by a creature named Gollum, Obsessed Stalker loses life equal to the amount of life you gained this turn.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

In Bolas's Clutches

Enchant permanent
You control enchanted permanent.
Enchanted permanent is legendary.

Unlikely Aid

Target creature gets +2/+0 and gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)