Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Ezzaroot Channeler

Reach
Creature spells you cast cost {X} less to cast, where X is the amount of life you gained this turn.
{T}: You gain 2 life.

Field-Tested Frying Pan

When Field-Tested Frying Pan enters, create a Food token, then create a 1/1 white Halfling creature token and attach Field-Tested Frying Pan to it.
Equipped creature has "Whenever you gain life, this creature gets +X/+X until end of turn, where X is the amount of life you gained."
Equip {2}

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Rodolf Duskbringer

Flying, deathtouch, lifelink
Whenever you gain life, Rodolf Duskbringer gains indestructible until end of turn.
At the beginning of your end step, you may pay {1}{W/B}. When you do, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Cradle of Vitality

Whenever you gain life, you may pay {1}{W}. If you do, put a +1/+1 counter on target creature for each 1 life you gained.

Celestial Mantle

Enchant creature
Enchanted creature gets +3/+3.
Whenever enchanted creature deals combat damage to a player, double its controller's life total.

Stream of Life

Treebeard, Gracious Host

Trample, ward {2}
When Treebeard, Gracious Host enters, create two Food tokens.
Whenever you gain life, put that many +1/+1 counters on target Halfling or Treefolk.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Bilbo, Birthday Celebrant

If you would gain life, you gain that much life plus 1 instead.
{2}{W}{B}{G}, {T}, Exile Bilbo, Birthday Celebrant: Search your library for any number of creature cards, put them onto the battlefield, then shuffle. Activate only if you have 111 or more life.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Light of Promise

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Accomplished Alchemist

{T}: Add one mana of any color.
{T}: Add X mana of any one color, where X is the amount of life you gained this turn.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Knight of Dawn's Light

First strike
If you would gain life, you gain that much life plus 1 instead.
{1}{W}: Knight of Dawn's Light gets +1/+1 until end of turn.

Honor Troll

Vigilance
If you would gain life, you gain that much life plus 1 instead.
Honor Troll gets +2/+1 as long as you have 25 or more life.

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
This creature gets +2/+2 as long as you have 25 or more life.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.