Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Oppression

Whenever a player casts a spell, that player discards a card.

Undercity's Embrace

Target opponent sacrifices a creature of their choice. If you control a creature with power 4 or greater, you gain 4 life.

Demon's Disciple

When Demon's Disciple enters, each player sacrifices a creature or planeswalker of their choice.

Fleshbag Marauder

When Fleshbag Marauder enters, each player sacrifices a creature of their choice.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Skullslither Worm

When Skullslither Worm enters, each opponent discards a card. For each opponent who can't, put two +1/+1 counters on Skullslither Worm.

Braids's Frightful Return

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — You may sacrifice a creature. If you do, each opponent discards a card.
II — Return target creature card from your graveyard to your hand.
III — Target opponent may sacrifice a nonland, nontoken permanent of their choice. If they don't, they lose 2 life and you draw a card.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Sibsig Icebreakers

When Sibsig Icebreakers enters, each player discards a card.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Swamp

Eriette's Whisper

Target opponent discards two cards. Create a Wicked Role token attached to up to one target creature you control. (If you control another Role on it, put that one into the graveyard. Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Tinybones Joins Up

When Tinybones Joins Up enters, any number of target players each discard a card.
Whenever a legendary creature you control enters, any number of target players each mill a card and lose 1 life.

Nezumi Informant

When Nezumi Informant enters, each opponent discards a card.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Mind Rot

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Hopeless Nightmare

When Hopeless Nightmare enters, each opponent discards a card and loses 2 life.
When Hopeless Nightmare is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice Hopeless Nightmare.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Burglar Rat

When this creature enters, each opponent discards a card.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Temple of the Dead

(Transforms from Aclazotz, Deepest Betrayal.)
{T}: Add {B}.
{2}{B}, {T}: Transform Temple of the Dead. Activate only if a player has one or fewer cards in hand and only as a sorcery.

Aclazotz, Deepest Betrayal

Flying, lifelink
Whenever Aclazotz attacks, each opponent discards a card. For each opponent who can't, you draw a card.
Whenever an opponent discards a land card, create a 1/1 black Bat creature token with flying.
When Aclazotz dies, return it to the battlefield tapped and transformed under its owner's control.

Aclazotz, Deepest Betrayal // Temple of the Dead

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When Tithing Blade enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Join the Dead

Target creature gets -5/-5 until end of turn.
Descend 4 — That creature gets -10/-10 until end of turn instead if there are four or more permanent cards in your graveyard.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Mephitic Vapors

All creatures get -1/-1 until end of turn.
Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Despise

Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.

Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Sol Ring

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Bloodtithe Collector

Flying
When this creature enters, if an opponent lost life this turn, each opponent discards a card.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Murder

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Extract a Confession

As an additional cost to cast this spell, you may collect evidence 6. (Exile cards with total mana value 6 or greater from your graveyard.)
Each opponent sacrifices a creature of their choice. If evidence was collected, instead each opponent sacrifices a creature with the greatest power among creatures they control.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Virus Beetle

When Virus Beetle enters, each opponent discards a card.

Ego Drain

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card. If you don't control a Faerie, exile a card from your hand.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Mindslicer

When Mindslicer dies, each player discards their hand.

The Eldest Reborn

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Each opponent sacrifices a creature or planeswalker of their choice.
II — Each opponent discards a card.
III — Put target creature or planeswalker card from a graveyard onto the battlefield under your control.

Dark Ritual

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Miasmic Mummy

When Miasmic Mummy enters, each player discards a card.

Delirium Skeins

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Divest

Target player reveals their hand. You choose an artifact or creature card from it. That player discards that card.