Light of Promise

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Unstoppable Slasher

Deathtouch
Whenever Unstoppable Slasher deals combat damage to a player, they lose half their life, rounded up.
When Unstoppable Slasher dies, if it had no counters on it, return it to the battlefield tapped under its owner's control with two stun counters on it.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Varragoth, Bloodsky Sire

Deathtouch
Boast — {1}{B}: Target player searches their library for a card, then shuffles and puts that card on top. (Activate only if this creature attacked this turn and only once each turn.)

Scytheclaw

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Plains

Faith's Fetters

Enchant permanent
When Faith's Fetters enters, you gain 4 life.
Enchanted permanent can't attack or block, and its activated abilities can't be activated unless they're mana abilities.

Preacher of the Schism

Deathtouch
Whenever Preacher of the Schism attacks the player with the most life or tied for most life, create a 1/1 white Vampire creature token with lifelink.
Whenever Preacher of the Schism attacks while you have the most life or are tied for most life, you draw a card and you lose 1 life.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Arcane Signet

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

True Conviction

Creatures you control have double strike and lifelink.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Sol Ring

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Surge of Salvation

You and permanents you control gain hexproof until end of turn. Prevent all damage that black and/or red sources would deal to creatures you control this turn.

Gollum, Obsessed Stalker

Skulk (This creature can't be blocked by creatures with greater power.)
At the beginning of your end step, each opponent dealt combat damage this game by a creature named Gollum, Obsessed Stalker loses life equal to the amount of life you gained this turn.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Exterminatus

Nonland permanents your opponents control lose indestructible until end of turn.
Destroy all nonland permanents.

Kaya's Guile

Choose two —
• Each opponent sacrifices a creature of their choice.
• Exile all opponents' graveyards.
• Create a 1/1 white and black Spirit creature token with flying.
• You gain 4 life.
Entwine {3} (Choose all if you pay the entwine cost.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Thriving Moor

Thriving Moor enters tapped. As it enters, choose a color other than black.
{T}: Add {B} or one mana of the chosen color.

Phyrexian Missionary

Kicker {1}{B} (You may pay an additional {1}{B} as you cast this spell.)
Lifelink
When Phyrexian Missionary enters, if it was kicked, return target creature card from your graveyard to your hand.

Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Vindicate

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Swamp

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Valorous Stance

Choose one —
• Target creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
• Destroy target creature with toughness 4 or greater.

Brokers Hideout

When Brokers Hideout enters, sacrifice it. When you do, search your library for a basic Forest, Plains, or Island card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Sunlit Marsh

({T}: Add {W} or {B}.)
Sunlit Marsh enters tapped.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Trailblazer's Boots

Equipped creature has nonbasic landwalk. (It can't be blocked as long as defending player controls a nonbasic land.)
Equip {2}

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Chant of Vitu-Ghazi

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Prevent all damage that would be dealt by creatures this turn. You gain life equal to the damage prevented this way.

Make a Stand

Creatures you control get +1/+0 and gain indestructible until end of turn. (Damage and effects that say "destroy" don't destroy them.)

Sower of Discord

Flying
As Sower of Discord enters, choose two players.
Whenever damage is dealt to one of the chosen players, the other chosen player also loses that much life.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Riveteers Overlook

When Riveteers Overlook enters, sacrifice it. When you do, search your library for a basic Swamp, Mountain, or Forest card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Silverquill Campus

Silverquill Campus enters tapped.
{T}: Add {W} or {B}.
{4}, {T}: Scry 1.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Awakening Hall

When you unlock this door, return all creature cards from your graveyard to the battlefield.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Funeral Room

Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Funeral Room // Awakening Hall

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Parasitic Impetus

Enchant creature
Enchanted creature gets +2/+2 and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
Whenever enchanted creature attacks, its controller loses 2 life and you gain 2 life.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Virtus the Veiled

Partner with Gorm the Great (When this creature enters, target player may put Gorm into their hand from their library, then shuffle.)
Deathtouch
Whenever Virtus the Veiled deals combat damage to a player, that player loses half their life, rounded up.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

High Priest of Penance

Whenever High Priest of Penance is dealt damage, you may destroy target nonland permanent.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Nearheath Pilgrim

Soulbond (You may pair this creature with another unpaired creature when either enters. They remain paired for as long as you control both of them.)
As long as Nearheath Pilgrim is paired with another creature, both creatures have lifelink.

Conqueror's Flail

Equipped creature gets +1/+1 for each color among permanents you control.
As long as Conqueror's Flail is attached to a creature, your opponents can't cast spells during your turn.
Equip {2}