Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

Vraska, Golgari Queen

+2: You may sacrifice another permanent. If you do, you gain 1 life and draw a card.
−3: Destroy target nonland permanent with mana value 3 or less.
−9: You get an emblem with "Whenever a creature you control deals combat damage to a player, that player loses the game."

Shatter the Oath

Destroy target creature or enchantment. Create a Wicked Role token attached to up to one target creature you control. (If you control another Role on it, put that one into the graveyard. Enchanted creature gets +1/+1. When this Aura is put into a graveyard, each opponent loses 1 life.)

Early Winter

Choose one —
• Exile target creature.
• Target opponent exiles an enchantment they control.

Force of Vigor

If it's not your turn, you may exile a green card from your hand rather than pay this spell's mana cost.
Destroy up to two target artifacts and/or enchantments.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Nettle Guard

Valiant — Whenever Nettle Guard becomes the target of a spell or ability you control for the first time each turn, it gets +0/+2 until end of turn.
{1}, Sacrifice Nettle Guard: Destroy target artifact or enchantment.

Bitter Triumph

As an additional cost to cast this spell, discard a card or pay 3 life.
Destroy target creature or planeswalker.

Damnation

Destroy all creatures. They can't be regenerated.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Abrupt Decay

This spell can't be countered.
Destroy target nonland permanent with mana value 3 or less.

Abrade

Choose one —
• Abrade deals 3 damage to target creature.
• Destroy target artifact.

Rip Apart

Choose one —
• Rip Apart deals 3 damage to target creature or planeswalker.
• Destroy target artifact or enchantment.

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Shriekmaw

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
When Shriekmaw enters, destroy target nonartifact, nonblack creature.
Evoke {1}{B} (You may cast this spell for its evoke cost. If you do, it's sacrificed when it enters.)

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Reclamation Sage

When this creature enters, you may destroy target artifact or enchantment.

Unsummon

Return target creature to its owner's hand.

Vandalblast

Destroy target artifact you don't control.
Overload {4}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

March of Otherworldly Light

As an additional cost to cast this spell, you may exile any number of white cards from your hand. This spell costs {2} less to cast for each card exiled this way.
Exile target artifact, creature, or enchantment with mana value X or less.

Loran of the Third Path

Vigilance
When Loran of the Third Path enters, destroy up to one target artifact or enchantment.
{T}: You and target opponent each draw a card.

Savor

Target creature gets -2/-2 until end of turn. Create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Run Away Together

Choose two target creatures controlled by different players. Return those creatures to their owners' hands.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Repel Calamity

Destroy target creature with power or toughness 4 or greater.

Bedevil

Destroy target artifact, creature, or planeswalker.

Disenchant

Terminate

Destroy target creature. It can't be regenerated.

Krosan Grip

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Destroy target artifact or enchantment.

Season of Gathering

Choose up to five {P} worth of modes. You may choose the same mode more than once.
{P} — Put a +1/+1 counter on a creature you control. It gains vigilance and trample until end of turn.
{P}{P} — Choose artifact or enchantment. Destroy all permanents of the chosen type.
{P}{P}{P} — Draw cards equal to the greatest power among creatures you control.

Terashi's Grasp

Destroy target artifact or enchantment. You gain life equal to its mana value.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Terastodon

When Terastodon enters, you may destroy up to three target noncreature permanents. For each permanent put into a graveyard this way, its controller creates a 3/3 green Elephant creature token.

Soporific Springs

As Soporific Springs enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {U}.

Sink into Stupor

Return target spell or nonland permanent an opponent controls to its owner's hand.

Sink into Stupor // Soporific Springs

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Hullbreaker Horror

Flash
This spell can't be countered.
Whenever you cast a spell, choose up to one —
• Return target spell you don't control to its owner's hand.
• Return target nonland permanent to its owner's hand.

Pawpatch Formation

Choose one —
• Destroy target creature with flying.
• Destroy target enchantment.
• Draw a card. Create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Tidecaller Mentor

Menace
Threshold — When Tidecaller Mentor enters, if seven or more cards are in your graveyard, return up to one target nonland permanent to its owner's hand.

Starfall Invocation

Gift a card (You may promise an opponent a gift as you cast this spell. If you do, they draw a card before its other effects.)
Destroy all creatures. If the gift was promised, return a creature card put into your graveyard this way to the battlefield under your control.

Abzan Charm

Choose one —
• Exile target creature with power 3 or greater.
• You draw two cards and you lose 2 life.
• Distribute two +1/+1 counters among one or two target creatures.

Agate Assault

Choose one —
• Agate Assault deals 4 damage to target creature. If that creature would die this turn, exile it instead.
• Exile target artifact.

Light of Hope

Choose one —
• You gain 4 life.
• Destroy target enchantment.
• Put a +1/+1 counter on target creature.

Noxious Gearhulk

Menace
When Noxious Gearhulk enters, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Glissa Sunslayer

First strike, deathtouch
Whenever Glissa Sunslayer deals combat damage to a player, choose one —
• You draw a card and you lose 1 life.
• Destroy target enchantment.
• Remove up to three counters from target permanent.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Deem Inferior

This spell costs {1} less to cast for each card you've drawn this turn.
The owner of target nonland permanent puts it into their library second from the top or on the bottom.

Raise the Palisade

Choose a creature type. Return all creatures that aren't of the chosen type to their owners' hands.

Otawara, Soaring City

{T}: Add {U}.
Channel — {3}{U}, Discard Otawara, Soaring City: Return target artifact, creature, enchantment, or planeswalker to its owner's hand. This ability costs {1} less to activate for each legendary creature you control.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Naturalize

Solitude

Flash
Lifelink
When Solitude enters, exile up to one other target creature. That creature's controller gains life equal to its power.
Evoke—Exile a white card from your hand.

Golgari Charm

Choose one —
• All creatures get -1/-1 until end of turn.
• Destroy target enchantment.
• Regenerate each creature you control.

Putrefy

Destroy target artifact or creature. It can't be regenerated.

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Fell

Meteor Golem

When this creature enters, destroy target nonland permanent an opponent controls.

Venser, Shaper Savant

Flash (You may cast this spell any time you could cast an instant.)
When Venser, Shaper Savant enters, return target spell or permanent to its owner's hand.

Angelic Ascension

Exile target creature or planeswalker. Its controller creates a 4/4 white Angel creature token with flying.

Nature's Claim

Destroy target artifact or enchantment. Its controller gains 4 life.

Aether Adept

When Aether Adept enters, return target creature to its owner's hand.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Dire Downdraft

This spell costs {1} less to cast if it targets an attacking or tapped creature.
Target creature's owner puts it on their choice of the top or bottom of their library.

Murder

Go for the Throat

Prismatic Ending

Converge — Exile target nonland permanent if its mana value is less than or equal to the number of colors of mana spent to cast this spell.

Fiery Confluence

Choose three. You may choose the same mode more than once.
• Fiery Confluence deals 1 damage to each creature.
• Fiery Confluence deals 2 damage to each opponent.
• Destroy target artifact.

Revoke Existence

Return to Nature

Choose one —
• Destroy target artifact.
• Destroy target enchantment.
• Exile target card from a graveyard.

Calamitous Tide

Return up to two target creatures to their owners' hands. Draw two cards, then discard a card.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Ertai Resurrected

Flash
When Ertai Resurrected enters, choose up to one —
• Counter target spell, activated ability, or triggered ability. Its controller draws a card.
• Destroy another target creature or planeswalker. Its controller draws a card.

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Infernal Grasp

Destroy target creature. You lose 2 life.

Into the Flood Maw

Gift a tapped Fish (You may promise an opponent a gift as you cast this spell. If you do, they create a tapped 1/1 blue Fish creature token before its other effects.)
Return target creature an opponent controls to its owner's hand. If the gift was promised, instead return target nonland permanent an opponent controls to its owner's hand.

Aura Shards

Whenever a creature you control enters, you may destroy target artifact or enchantment.

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Hivespine Wolverine

When Hivespine Wolverine enters, choose one —
• Put a +1/+1 counter on target creature you control.
• Hivespine Wolverine fights target creature token.
• Destroy target artifact or enchantment.

Doom Blade

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Aetherize

Return all attacking creatures to their owner's hand.

Gleeful Demolition

Destroy target artifact. If you controlled that artifact, create three 1/1 red Phyrexian Goblin creature tokens.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Boseiju, Who Endures

{T}: Add {G}.
Channel — {1}{G}, Discard Boseiju, Who Endures: Destroy target artifact, enchantment, or nonbasic land an opponent controls. That player may search their library for a land card with a basic land type, put it onto the battlefield, then shuffle. This ability costs {1} less to activate for each legendary creature you control.

Void Rend

This spell can't be countered.
Destroy target nonland permanent.

Fatal Push

Destroy target creature if it has mana value 2 or less.
Revolt — Destroy that creature if it has mana value 4 or less instead if a permanent you controlled left the battlefield this turn.

Destroy Evil

Choose one —
• Destroy target creature with toughness 4 or greater.
• Destroy target enchantment.

Mortify

Hull Breach

Choose one —
• Destroy target artifact.
• Destroy target enchantment.
• Destroy target artifact and target enchantment.

Ravenous Chupacabra

When Ravenous Chupacabra enters, destroy target creature an opponent controls.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Wick's Patrol

When Wick's Patrol enters, mill three cards. When you do, target creature an opponent controls gets -X/-X until end of turn, where X is the greatest mana value among cards in your graveyard.

Sanctify

Destroy target artifact or enchantment. You gain 3 life.

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When Murderous Rider dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Season of the Burrow

Choose up to five {P} worth of modes. You may choose the same mode more than once.
{P} — Create a 1/1 white Rabbit creature token.
{P}{P} — Exile target nonland permanent. Its controller draws a card.
{P}{P}{P} — Return target permanent card with mana value 3 or less from your graveyard to the battlefield with an indestructible counter on it.