Epic Struggle

At the beginning of your upkeep, if you control twenty or more creatures, you win the game.

Flare of Faith

Target creature gets +2/+2 until end of turn. If it's a Human, instead it gets +3/+3 and gains indestructible until end of turn.

Darksteel Reactor

Indestructible (Effects that say "destroy" don't destroy this artifact.)
At the beginning of your upkeep, you may put a charge counter on Darksteel Reactor.
When Darksteel Reactor has twenty or more charge counters on it, you win the game.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Trelasarra, Moon Dancer

Whenever you gain life, put a +1/+1 counter on Trelasarra, Moon Dancer and scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Whiptongue Hydra

Reach
When Whiptongue Hydra enters, destroy all creatures with flying. Put a +1/+1 counter on Whiptongue Hydra for each creature destroyed this way.

Essence Warden

Whenever another creature enters, you gain 1 life.

Brenard, Ginger Sculptor

Each creature you control that's a Food or a Golem gets +2/+2 and has trample.
Whenever another nontoken creature you control dies, you may exile it. If you do, create a token that's a copy of that creature, except it's a 1/1 Food Golem artifact creature in addition to its other types and it has "{2}, {T}, Sacrifice this artifact: You gain 3 life."

Shanna, Purifying Blade

Lifelink
At the beginning of your end step, you may pay {X}. If you do, draw X cards. X can't be greater than the amount of life you gained this turn.

Mechanized Production

Enchant artifact you control
At the beginning of your upkeep, create a token that's a copy of enchanted artifact. Then if you control eight or more artifacts with the same name as one another, you win the game.

Soul Warden

Helix Pinnacle

Shroud (This enchantment can't be the target of spells or abilities.)
{X}: Put X tower counters on Helix Pinnacle.
At the beginning of your upkeep, if there are 100 or more tower counters on Helix Pinnacle, you win the game.

Maze's End

Maze's End enters tapped.
{T}: Add {C}.
{3}, {T}, Return Maze's End to its owner's hand: Search your library for a Gate card, put it onto the battlefield, then shuffle. If you control ten or more Gates with different names, you win the game.

Bane of Progress

When Bane of Progress enters, destroy all artifacts and enchantments. Put a +1/+1 counter on Bane of Progress for each permanent destroyed this way.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Steelbane Hydra

Steelbane Hydra enters with X +1/+1 counters on it.
{2}{G}, Remove a +1/+1 counter from Steelbane Hydra: Destroy target artifact or enchantment.

Biovisionary

At the beginning of the end step, if you control four or more creatures named Biovisionary, you win the game.

Azor's Elocutors

At the beginning of your upkeep, put a filibuster counter on Azor's Elocutors. Then if Azor's Elocutors has five or more filibuster counters on it, you win the game.
Whenever a source deals damage to you, remove a filibuster counter from Azor's Elocutors.

The Ozolith

Whenever a creature you control leaves the battlefield, if it had counters on it, put those counters on The Ozolith.
At the beginning of combat on your turn, if The Ozolith has counters on it, you may move all counters from The Ozolith onto target creature.

Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Kros, Defense Contractor

At the beginning of your upkeep, put a shield counter on target creature an opponent controls.
Whenever you put one or more counters on a creature you don't control, tap that creature and goad it. It gains trample until your next turn. (Until your next turn, that creature attacks each combat if able and attacks a player other than you if able.)

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Simic Ascendancy

{1}{G}{U}: Put a +1/+1 counter on target creature you control.
Whenever one or more +1/+1 counters are put on a creature you control, put that many growth counters on Simic Ascendancy.
At the beginning of your upkeep, if Simic Ascendancy has twenty or more growth counters on it, you win the game.

The Millennium Calendar

Whenever you untap one or more permanents during your untap step, put that many time counters on The Millennium Calendar.
{2}, {T}: Double the number of time counters on The Millennium Calendar.
When there are 1,000 or more time counters on The Millennium Calendar, sacrifice it and each opponent loses 1,000 life.