Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Urza, Lord High Artificer

When Urza, Lord High Artificer enters, create a 0/0 colorless Construct artifact creature token with "This creature gets +1/+1 for each artifact you control."
Tap an untapped artifact you control: Add {U}.
{5}: Shuffle your library, then exile the top card. Until end of turn, you may play that card without paying its mana cost.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Tezzeret, Master of the Bridge

Creature and planeswalker spells you cast have affinity for artifacts. (They cost {1} less to cast for each artifact you control.)
+2: Tezzeret, Master of the Bridge deals X damage to each opponent, where X is the number of artifacts you control. You gain X life.
−3: Return target artifact card from your graveyard to your hand.
−8: Exile the top ten cards of your library. Put all artifact cards from among them onto the battlefield.

Tezzeret the Schemer

+1: Create a colorless artifact token named Etherium Cell with "{T}, Sacrifice this artifact: Add one mana of any color."
−2: Target creature gets +X/-X until end of turn, where X is the number of artifacts you control.
−7: You get an emblem with "At the beginning of combat on your turn, target artifact you control becomes an artifact creature with base power and toughness 5/5."

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.