Ulamog, the Ceaseless Hunger

When you cast this spell, exile two target permanents.
Indestructible
Whenever Ulamog, the Ceaseless Hunger attacks, defending player exiles the top twenty cards of their library.

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

Emrakul, the World Anew

When you cast this spell, gain control of all creatures target player controls.
Flying, protection from spells and from permanents that were cast this turn
When Emrakul, the World Anew leaves the battlefield, sacrifice all creatures you control.
Madness—Pay six {C}.

Emrakul, the Promised End

This spell costs {1} less to cast for each card type among cards in your graveyard.
When you cast this spell, you gain control of target opponent during that player's next turn. After that turn, that player takes an extra turn.
Flying, trample, protection from instants

It That Betrays

Annihilator 2 (Whenever this creature attacks, defending player sacrifices two permanents of their choice.)
Whenever an opponent sacrifices a nontoken permanent, put that card onto the battlefield under your control.

Kozilek, the Great Distortion

When you cast this spell, if you have fewer than seven cards in hand, draw cards equal to the difference.
Menace
Discard a card with mana value X: Counter target spell with mana value X.

Kozilek, Butcher of Truth

When you cast this spell, draw four cards.
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Kozilek, Butcher of Truth is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Ulamog, the Defiler

When you cast this spell, target opponent exiles the top half of their library, rounded up.
Ward—Sacrifice two permanents.
Ulamog, the Defiler enters with a number of +1/+1 counters on it equal to the greatest mana value among cards in exile.
Ulamog has annihilator X, where X is the number of +1/+1 counters on it.

Kozilek, the Broken Reality

When you cast this spell, up to two target players each manifest two cards from their hands. For each card manifested this way, you draw a card. (To manifest a card, put it onto the battlefield face down as a 2/2 creature. Turn it face up any time for its mana cost if it's a creature card.)
Other colorless creatures you control get +3/+2.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

The Infamous Cruelclaw

Menace
Whenever The Infamous Cruelclaw deals combat damage to a player, exile cards from the top of your library until you exile a nonland card. You may cast that card by discarding a card rather than paying its mana cost.