Ayli, Eternal Pilgrim

Deathtouch
{1}, Sacrifice another creature: You gain life equal to the sacrificed creature's toughness.
{1}{W}{B}, Sacrifice another creature: Exile target nonland permanent. Activate only if you have at least 10 life more than your starting life total.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Harvester of Souls

Deathtouch
Whenever another nontoken creature dies, you may draw a card.

Archangel of Thune

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Whenever you gain life, put a +1/+1 counter on each creature you control.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Sol Ring

Cloak of the Bat

Equipped creature has flying and haste.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Corrupt

Corrupt deals damage to any target equal to the number of Swamps you control. You gain life equal to the damage dealt this way.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Arcane Signet

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

One Thousand Lashes

Enchant creature
Enchanted creature can't attack or block, and its activated abilities can't be activated.
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Remorseless Punishment

Target opponent loses 5 life unless that player discards two cards or sacrifices a creature or planeswalker. Repeat this process once.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Archon of Redemption

Flying
Whenever Archon of Redemption or another creature you control with flying enters, you may gain life equal to that creature's power.

Sign in Blood

Target player draws two cards and loses 2 life.

Iridescent Vinelasher

Offspring {2} (You may pay an additional {2} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Landfall — Whenever a land you control enters, this creature deals 1 damage to target opponent.

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Murder

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Gift of Orzhova

Enchant creature
Enchanted creature gets +1/+1 and has flying and lifelink.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Quag Vampires

Multikicker {1}{B} (You may pay an additional {1}{B} any number of times as you cast this spell.)
Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
Quag Vampires enters with a +1/+1 counter on it for each time it was kicked.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Barbed Servitor

Indestructible
When Barbed Servitor enters, suspect it. (It has menace and can't block.)
Whenever Barbed Servitor deals combat damage to a player, you draw a card and you lose 1 life.
Whenever Barbed Servitor is dealt damage, target opponent loses that much life.

Darkstar Augur

Offspring {B} (You may pay an additional {B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Lunar Convocation

At the beginning of your end step, if you gained life this turn, each opponent loses 1 life.
At the beginning of your end step, if you gained and lost life this turn, create a 1/1 black Bat creature token with flying.
{1}{B}, Pay 2 life: Draw a card.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Sorin the Mirthless

+1: Look at the top card of your library. You may reveal that card and put it into your hand. If you do, you lose life equal to its mana value.
−2: Create a 2/3 black Vampire creature token with flying and lifelink.
−7: Sorin the Mirthless deals 13 damage to any target. You gain 13 life.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Executioner's Hood

Equipped creature has intimidate. (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.