The Mindskinner

The Mindskinner can't be blocked.
If a source you control would deal damage to an opponent, prevent that damage and each opponent mills that many cards.

Fractured Sanity

Each opponent mills fourteen cards.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Fractured Sanity, each opponent mills four cards.

Island

Jace's Phantasm

Flying
Jace's Phantasm gets +4/+4 as long as an opponent has ten or more cards in their graveyard.

Sanity Grinding

Chroma — Reveal the top ten cards of your library. For each blue mana symbol in the mana costs of the revealed cards, target opponent mills a card. Then put the cards you revealed this way on the bottom of your library in any order.