Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Cunning Rhetoric

Whenever an opponent attacks you and/or one or more planeswalkers you control, exile the top card of that player's library. You may play that card for as long as it remains exiled, and you may spend mana as though it were mana of any color to cast it.

Dark Ritual

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Cover of Darkness

As Cover of Darkness enters, choose a creature type.
Creatures of the chosen type have fear. (They can't be blocked except by artifact creatures and/or black creatures.)

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Disciple of the Vault

Whenever an artifact is put into a graveyard from the battlefield, you may have target opponent lose 1 life.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Accursed Marauder

When Accursed Marauder enters, each player sacrifices a nontoken creature of their choice.

Damnation

Destroy all creatures. They can't be regenerated.

Mirkwood Bats

Flying
Whenever you create or sacrifice a token, each opponent loses 1 life.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Swamp

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control of their choice, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Reassembling Skeleton

{1}{B}: Return Reassembling Skeleton from your graveyard to the battlefield tapped.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.