Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Phage the Untouchable

When Phage the Untouchable enters, if you didn't cast it from your hand, you lose the game.
Whenever Phage deals combat damage to a creature, destroy that creature. It can't be regenerated.
Whenever Phage deals combat damage to a player, that player loses the game.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Maze's End

This land enters tapped.
{T}: Add {C}.
{3}, {T}, Return this land to its owner's hand: Search your library for a Gate card, put it onto the battlefield, then shuffle. If you control ten or more Gates with different names, you win the game.

Thassa's Oracle

When Thassa's Oracle enters, look at the top X cards of your library, where X is your devotion to blue. Put up to one of them on top of your library and the rest on the bottom of your library in a random order. If X is greater than or equal to the number of cards in your library, you win the game. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)

Triskaidekaphile

You have no maximum hand size.
At the beginning of your upkeep, if you have exactly thirteen cards in your hand, you win the game.
{3}{U}: Draw a card.

The Cinematic Phoenix

Flying, haste, protection from red
{1}, {T}: Return target legendary creature card from your graveyard to the battlefield.
Tap six untapped creatures you control: Return The Cinematic Phoenix from your graveyard to the battlefield. If you tapped six legendary creatures this way, you win the game.

The Cheese Stands Alone

When you control no permanents other than The Cheese Stands Alone and have no cards in hand, you win the game.

Mirrodin Besieged

As Mirrodin Besieged enters, choose Mirran or Phyrexian.
• Mirran — Whenever you cast an artifact spell, create a 1/1 colorless Myr artifact creature token.
• Phyrexian — At the beginning of your end step, draw a card, then discard a card. Then if there are fifteen or more artifact cards in your graveyard, target opponent loses the game.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Halo Fountain

{W}, {T}, Untap a tapped creature you control: Create a 1/1 green and white Citizen creature token.
{W}{W}, {T}, Untap two tapped creatures you control: Draw a card.
{W}{W}{W}{W}{W}, {T}, Untap fifteen tapped creatures you control: You win the game.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Barren Glory

At the beginning of your upkeep, if you control no permanents other than Barren Glory and have no cards in hand, you win the game.

Vessel of the All-Consuming

Trample
Whenever Vessel of the All-Consuming deals damage, put a +1/+1 counter on it.
Whenever Vessel of the All-Consuming deals damage to a player, if it has dealt 10 or more damage to that player this turn, they lose the game.

Hidetsugu Consumes All

(As this Saga enters and after your draw step, add a lore counter.)
I — Destroy each nonland permanent with mana value 1 or less.
II — Exile all graveyards.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Hidetsugu Consumes All // Vessel of the All-Consuming

Atemsis, All-Seeing

Flying
{2}{U}, {T}: Draw two cards, then discard a card.
Whenever Atemsis, All-Seeing deals damage to an opponent, you may reveal your hand. If cards with at least six different mana values are revealed this way, that player loses the game.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Darksteel Reactor

Indestructible (Effects that say "destroy" don't destroy this artifact.)
At the beginning of your upkeep, you may put a charge counter on Darksteel Reactor.
When Darksteel Reactor has twenty or more charge counters on it, you win the game.

Simic Ascendancy

{1}{G}{U}: Put a +1/+1 counter on target creature you control.
Whenever one or more +1/+1 counters are put on a creature you control, put that many growth counters on Simic Ascendancy.
At the beginning of your upkeep, if Simic Ascendancy has twenty or more growth counters on it, you win the game.

Baron Von Count

Baron Von Count enters with a doom counter on "5."
Whenever you cast a spell with the indicated numeral in its mana cost, text box, power, or toughness, move the doom counter one numeral to the left.
When the doom counter moves from "1," destroy target player and put that doom counter on "5."

Strixhaven Stadium

{T}: Add {C}. Put a point counter on Strixhaven Stadium.
Whenever a creature deals combat damage to you, remove a point counter from Strixhaven Stadium.
Whenever a creature you control deals combat damage to an opponent, put a point counter on Strixhaven Stadium. Then if it has ten or more point counters on it, remove them all and that player loses the game.

Twenty-Toed Toad

Your maximum hand size is twenty.
Whenever you attack with two or more creatures, put a +1/+1 counter on Twenty-Toed Toad and draw a card.
Whenever Twenty-Toed Toad attacks, you win the game if there are twenty or more counters on it or you have twenty or more cards in hand.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Helix Pinnacle

Shroud (This enchantment can't be the target of spells or abilities.)
{X}: Put X tower counters on Helix Pinnacle.
At the beginning of your upkeep, if there are 100 or more tower counters on Helix Pinnacle, you win the game.

Etrata, the Silencer

Etrata, the Silencer can't be blocked.
Whenever Etrata deals combat damage to a player, exile target creature that player controls and put a hit counter on that card. That player loses the game if they own three or more exiled cards with hit counters on them. Etrata's owner shuffles Etrata into their library.

Liliana's Contract

When Liliana's Contract enters, you draw four cards and you lose 4 life.
At the beginning of your upkeep, if you control four or more Demons with different names, you win the game.

Nicol Bolas, Dragon-God

Nicol Bolas, Dragon-God has all loyalty abilities of all other planeswalkers on the battlefield.
+1: You draw a card. Each opponent exiles a card from their hand or a permanent they control.
−3: Destroy target creature or planeswalker.
−8: Each opponent who doesn't control a legendary creature or planeswalker loses the game.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Yargle and Multani

Ixhel, Scion of Atraxa

Flying, vigilance, toxic 2
Corrupted — At the beginning of your end step, each opponent who has three or more poison counters exiles the top card of their library face down. You may look at and play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast those spells.

Battle of Wits

At the beginning of your upkeep, if you have 200 or more cards in your library, you win the game.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Door to Nothingness

Door to Nothingness enters tapped.
{W}{W}{U}{U}{B}{B}{R}{R}{G}{G}, {T}, Sacrifice Door to Nothingness: Target player loses the game.

Hive Mind

Whenever a player casts an instant or sorcery spell, each other player copies that spell. Each of those players may choose new targets for their copy.

Amulet of Quoz

Remove Amulet of Quoz from your deck before playing if you're not playing for ante.
{T}, Sacrifice Amulet of Quoz: Target opponent may ante the top card of their library. If they don't, you flip a coin. If you win the flip, that player loses the game. If you lose the flip, you lose the game. Activate only during your upkeep.

Frodo, Sauron's Bane

{W/B}{W/B}: If Frodo, Sauron's Bane is a Citizen, it becomes a Halfling Scout with base power and toughness 2/3 and lifelink.
{B}{B}{B}: If Frodo is a Scout, it becomes a Halfling Rogue with "Whenever this creature deals combat damage to a player, that player loses the game if the Ring has tempted you four or more times this game. Otherwise, the Ring tempts you."

Jace, Wielder of Mysteries

If you would draw a card while your library has no cards in it, you win the game instead.
+1: Target player mills two cards. Draw a card.
−8: Draw seven cards. Then if your library has no cards in it, you win the game.

Vraska, Golgari Queen

+2: You may sacrifice another permanent. If you do, you gain 1 life and draw a card.
−3: Destroy target nonland permanent with mana value 3 or less.
−9: You get an emblem with "Whenever a creature you control deals combat damage to a player, that player loses the game."

Revel in Riches

Whenever a creature an opponent controls dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
At the beginning of your upkeep, if you control ten or more Treasures, you win the game.

Celestial Convergence

Celestial Convergence enters with seven omen counters on it.
At the beginning of your upkeep, remove an omen counter from Celestial Convergence. If there are no omen counters on Celestial Convergence, the player with the highest life total wins the game. If two or more players are tied for highest life total, the game is a draw.

Now I Know My ABC's

At the beginning of your upkeep, if you control permanents with names that include all twenty-six letters of the English alphabet, you win the game.

The Deck of Many Things

{2}, {T}: Roll a d20 and subtract the number of cards in your hand. If the result is 0 or less, discard your hand.
1—9 | Return a card at random from your graveyard to your hand.
10—19 | Draw two cards.
20 | Put a creature card from any graveyard onto the battlefield under your control. When that creature dies, its owner loses the game.

Epic Struggle

At the beginning of your upkeep, if you control twenty or more creatures, you win the game.

Hellkite Tyrant

Flying, trample
Whenever Hellkite Tyrant deals combat damage to a player, gain control of all artifacts that player controls.
At the beginning of your upkeep, if you control twenty or more artifacts, you win the game.

Azor's Elocutors

At the beginning of your upkeep, put a filibuster counter on Azor's Elocutors. Then if Azor's Elocutors has five or more filibuster counters on it, you win the game.
Whenever a source deals damage to you, remove a filibuster counter from Azor's Elocutors.

Luck Bobblehead

{T}: Add one mana of any color.
{1}, {T}: Roll X six-sided dice, where X is the number of Bobbleheads you control. Create a tapped Treasure token for each even result. If you rolled 6 exactly seven times, you win the game.

Vraska the Unseen

+1: Until your next turn, whenever a creature deals combat damage to Vraska the Unseen, destroy that creature.
−3: Destroy target nonland permanent.
−7: Create three 1/1 black Assassin creature tokens with "Whenever this creature deals combat damage to a player, that player loses the game."

Topdeck the Halls

Decorated cards in your hand have miracle {S}. (Decorated cards include premiums, promos, and cards with alternate frames or art.)
At the beginning of your upkeep, if you control twelve or more decorated permanents, you win the game.

Sinner's Judgment

Enchant player
At the beginning of your upkeep, put a judgment counter on Sinner's Judgment. Then if there are three or more judgment counters on it, enchanted player loses the game.
If Sinner's Judgment would be put into a graveyard from anywhere, exile it instead.

Faithbound Judge

Defender, flying, vigilance
At the beginning of your upkeep, if Faithbound Judge has two or fewer judgment counters on it, put a judgment counter on it.
As long as Faithbound Judge has three or more judgment counters on it, it can attack as though it didn't have defender.
Disturb {5}{W}{W}

Faithbound Judge // Sinner's Judgment

Chance Encounter

Whenever you win a coin flip, put a luck counter on Chance Encounter.
At the beginning of your upkeep, if Chance Encounter has ten or more luck counters on it, you win the game.

Ersta, Friend to All

+1: Create a 1/1 Human Wizard creature token that's all colors.
−3: Choose a card name from among Enlightened Tutor, Mystical Tutor, Booster Tutor, Imperial Recruiter, and Worldly Tutor. Create a copy of the card with the chosen name. You may cast the copy without paying its mana cost.
−8: You get an emblem with "At the beginning of your upkeep, if you control twenty or more Wizards, you win the game."
Ersta, Friend to All can be your commander.

Vraska, Scheming Gorgon

+2: Creatures you control get +1/+0 until end of turn.
−3: Destroy target creature.
−10: Until end of turn, creatures you control gain deathtouch and "Whenever this creature deals damage to an opponent, that player loses the game."

Teferi's Tutelage

When Teferi's Tutelage enters, draw a card, then discard a card.
Whenever you draw a card, target opponent mills two cards. (They put the top two cards of their library into their graveyard.)

Vraska, Relic Seeker

+2: Create a 2/2 black Pirate creature token with menace.
−3: Destroy target artifact, creature, or enchantment. Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
−10: Target player's life total becomes 1.

Mayael's Aria

At the beginning of your upkeep, put a +1/+1 counter on each creature you control if you control a creature with power 5 or greater. Then you gain 10 life if you control a creature with power 10 or greater. Then you win the game if you control a creature with power 20 or greater.

Happily Ever After

When Happily Ever After enters, each player gains 5 life and draws a card.
At the beginning of your upkeep, if there are five colors among permanents you control, there are six or more card types among permanents you control and/or cards in your graveyard, and your life total is greater than or equal to your starting life total, you win the game.

Mechanized Production

Enchant artifact you control
At the beginning of your upkeep, create a token that's a copy of enchanted artifact. Then if you control eight or more artifacts with the same name as one another, you win the game.

Hedron Alignment

Hexproof
At the beginning of your upkeep, you may reveal your hand. If you do, you win the game if you own a card named Hedron Alignment in exile, in your hand, in your graveyard, and on the battlefield.
{1}{U}: Scry 1.

Coalition Victory

You win the game if you control a land of each basic land type and a creature of each color.

Ramses, Assassin Lord

Deathtouch
Other Assassins you control get +1/+1.
Whenever a player loses the game, if they were attacked this turn by an Assassin you controlled, you win the game.

The Millennium Calendar

Whenever you untap one or more permanents during your untap step, put that many time counters on The Millennium Calendar.
{2}, {T}: Double the number of time counters on The Millennium Calendar.
When there are 1,000 or more time counters on The Millennium Calendar, sacrifice it and each opponent loses 1,000 life.

Vorpal Sword

Equipped creature gets +2/+0 and has deathtouch.
{5}{B}{B}{B}: Until end of turn, Vorpal Sword gains "Whenever equipped creature deals combat damage to a player, that player loses the game."
Equip {B}{B}

Mortal Combat

At the beginning of your upkeep, if twenty or more creature cards are in your graveyard, you win the game.

Biovisionary

At the beginning of the end step, if you control four or more creatures named Biovisionary, you win the game.

As Luck Would Have It

Hexproof
Whenever you roll a die, put a number of luck counters on As Luck Would Have It equal to the result. Then if there are 100 or more luck counters on As Luck Would Have It, you win the game. (Count both rolls if you reroll a die.)

Form of the Approach of the Second Sun

When this enchantment enters, you gain 7 life. You become a card until you leave your library or that library is shuffled. Put yourself seventh from the top, balancing the cards on top of you on your head.
When you draw yourself, you win the game.
When one or more cards fall off your head, exile them and all cards on your head, then sacrifice this enchantment.