Getting

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Have

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Temple of Power

(Transforms from Ojer Axonil, Deepest Might.)
{T}: Add {R}.
{2}{R}, {T}: Transform Temple of Power. Activate only if red sources you controlled dealt 4 or more noncombat damage this turn and only as a sorcery.

Ojer Axonil, Deepest Might

Trample
If a red source you control would deal an amount of noncombat damage less than Ojer Axonil's power to an opponent, that source deals damage equal to Ojer Axonil's power instead.
When Ojer Axonil dies, return it to the battlefield tapped and transformed under its owner's control.

Ojer Axonil, Deepest Might // Temple of Power

Damnation

Destroy all creatures. They can't be regenerated.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature.

Sanguine Morass

Sanguine Morass enters tapped.
{T}: Add {B} or {R}.

Bloodsoaked Insight

This spell costs {1} less to cast for each 1 life your opponents have lost this turn.
Target opponent exiles the top three cards of their library. Until the end of your next turn, you may play those cards. If you cast a spell this way, mana of any type can be spent to cast it.

Bloodsoaked Insight // Sanguine Morass

Tibalt's Trickery

Counter target spell. Choose 1, 2, or 3 at random. Its controller mills that many cards, then exiles cards from the top of their library until they exile a nonland card with a different name than that spell. They may cast that card without paying its mana cost. Then they put the exiled cards on the bottom of their library in a random order.

Swamp

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Bedevil

Destroy target artifact, creature, or planeswalker.

Shivan Gorge

{T}: Add {C}.
{2}{R}, {T}: Shivan Gorge deals 1 damage to each opponent.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Withering Torment

Destroy target creature or enchantment. You lose 2 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Suspended Sentence

Destroy target creature an opponent controls. That player loses 3 life. Exile Suspended Sentence with three time counters on it.
Suspend 3—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Razorkin Needlehead

Razorkin Needlehead has first strike during your turn.
Whenever an opponent draws a card, Razorkin Needlehead deals 1 damage to them.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Sign in Blood

Target player draws two cards and loses 2 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Dark Ritual

Light Up the Stage

Spectacle {R} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Exile the top two cards of your library. Until the end of your next turn, you may play those cards.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Agadeem, the Undercrypt

As Agadeem, the Undercrypt enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {B}.

Agadeem's Awakening

Return from your graveyard to the battlefield any number of target creature cards that each have a different mana value X or less.

Agadeem's Awakening // Agadeem, the Undercrypt

Tainted Peak

{T}: Add {C}.
{T}: Add {B} or {R}. Activate only if you control a Swamp.

Arena of Glory

Arena of Glory enters tapped unless you control a Mountain.
{T}: Add {R}.
{R}, {T}, Exert Arena of Glory: Add {R}{R}. If that mana is spent on a creature spell, it gains haste until end of turn. (An exerted permanent won't untap during your next untap step.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Theater of Horrors

At the beginning of your upkeep, exile the top card of your library.
During your turn, if an opponent lost life this turn, you may play lands and cast spells from among cards exiled with Theater of Horrors.
{3}{R}: Theater of Horrors deals 1 damage to target opponent or planeswalker.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Blazemire Verge

{T}: Add {B}.
{T}: Add {R}. Activate only if you control a Swamp or a Mountain.

Rakdos, Lord of Riots

You can't cast this spell unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Kardur, Doomscourge

When Kardur, Doomscourge enters, until your next turn, creatures your opponents control attack each combat if able and attack a player other than you if able.
Whenever an attacking creature dies, each opponent loses 1 life and you gain 1 life.

Rakdos Signet

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Roiling Vortex

At the beginning of each player's upkeep, Roiling Vortex deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, Roiling Vortex deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Jeska's Will

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Add {R} for each card in target opponent's hand.
• Exile the top three cards of your library. You may play them this turn.

Ob Nixilis, Captive Kingpin

Flying, trample
Whenever one or more opponents each lose exactly 1 life, put a +1/+1 counter on Ob Nixilis, Captive Kingpin. Exile the top card of your library. Until your next end step, you may play that card.

Deflecting Swat

If you control a commander, you may cast this spell without paying its mana cost.
You may choose new targets for target spell or ability.

Infernal Grasp

Destroy target creature. You lose 2 life.

Valakut Stoneforge

Valakut Stoneforge enters tapped.
{T}: Add {R}.

Valakut Awakening

Put any number of cards from your hand on the bottom of your library, then draw that many cards plus one.

Valakut Awakening // Valakut Stoneforge

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Dragonskull Summit

Dragonskull Summit enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Ruby Medallion

Red spells you cast cost {1} less to cast.

Command Tower

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Rampaging Ferocidon

Menace
Players can't gain life.
Whenever another creature enters, Rampaging Ferocidon deals 1 damage to that creature's controller.

Gleeful Arsonist

Whenever an opponent casts a noncreature spell, Gleeful Arsonist deals damage equal to its power to that player.
Undying (When this creature dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Spinerock Knoll

Hideaway 4 (When this land enters, look at the top four cards of your library, exile one face down, then put the rest on the bottom in a random order.)
Spinerock Knoll enters tapped.
{T}: Add {R}.
{R}, {T}: You may play the exiled card without paying its mana cost if an opponent was dealt 7 or more damage this turn.

Terminate

Destroy target creature. It can't be regenerated.

Persistent Constrictor

At the beginning of each opponent's upkeep, they lose 1 life and you put a -1/-1 counter on up to one target creature they control.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Mountain

Florian, Voldaren Scion

First strike
At the beginning of each of your postcombat main phases, look at the top X cards of your library, where X is the total amount of life your opponents lost this turn. Exile one of those cards and put the rest on the bottom of your library in a random order. You may play the exiled card this turn.

Rug of Smothering

Flying
Whenever a player casts a spell, they lose 1 life for each spell they've cast this turn.

Sol Ring

Valgavoth's Lair

Hexproof
Valgavoth's Lair enters tapped. As it enters, choose a color.
{T}: Add one mana of the chosen color.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

Ritual Chamber

When you unlock this door, create a 6/6 black Demon creature token with flying.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Unholy Annex

At the beginning of your end step, draw a card. If you control a Demon, each opponent loses 2 life and you gain 2 life. Otherwise, you lose 2 life.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Unholy Annex // Ritual Chamber

Grab the Prize

As an additional cost to cast this spell, discard a card.
Draw two cards. If the discarded card wasn't a land card, Grab the Prize deals 2 damage to each opponent.

Malakir Mire

Malakir Mire enters tapped.
{T}: Add {B}.

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Shadowblood Ridge

Witch's Clinic

{T}: Add {C}.
{2}, {T}: Target commander gains lifelink until end of turn.

Fell Mire

As Fell Mire enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {B}.

Fell the Profane

Fell the Profane // Fell Mire

Restless Vents

Restless Vents enters tapped.
{T}: Add {B} or {R}.
{1}{B}{R}: Until end of turn, Restless Vents becomes a 2/3 black and red Insect creature with menace. It's still a land.
Whenever Restless Vents attacks, you may discard a card. If you do, draw a card.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Valgavoth, Terror Eater

Flying, lifelink
Ward—Sacrifice three nonland permanents.
If a card you didn't control would be put into an opponent's graveyard from anywhere, exile it instead.
During your turn, you may play cards exiled with Valgavoth. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Valgavoth, Harrower of Souls

Flying
Ward—Pay 2 life.
Whenever an opponent loses life for the first time during each of their turns, put a +1/+1 counter on Valgavoth, Harrower of Souls and draw a card.