Homicidal Seclusion

As long as you control exactly one creature, that creature gets +3/+1 and has lifelink.

Night's Whisper

Blight Sickle

Equipped creature gets +1/+0 and has wither. (It deals damage to creatures in the form of -1/-1 counters.)
Equip {2}

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Valgavoth, Harrower of Souls

Flying
Ward—Pay 2 life.
Whenever an opponent loses life for the first time during each of their turns, put a +1/+1 counter on Valgavoth and draw a card.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Subversion

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Rug of Smothering

Flying
Whenever a player casts a spell, they lose 1 life for each spell they've cast this turn.

Rakdos, Lord of Riots

You can't cast Rakdos unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Bearded Axe

Equipped creature gets +1/+1 for each Dwarf, Equipment, and/or Vehicle you control.
Equip {2}

Sign in Blood

Target player draws two cards and loses 2 life.

Rankle and Torbran

Flying, first strike, haste
Whenever Rankle and Torbran deals combat damage to a player or battle, choose any number —
• Each player creates a Treasure token.
• Each player sacrifices a creature of their choice.
• If a source would deal damage to a player or battle this turn, it deals that much damage plus 2 instead.

Altar of the Pantheon

Your devotion to each color and each combination of colors is increased by one.
{T}: Add one mana of any color. If you control a God, a Demigod, or a legendary enchantment, you gain 1 life.

Basilisk Collar

Equipped creature has deathtouch and lifelink. (Any amount of damage it deals to a creature is enough to destroy it. Damage dealt by this creature also causes you to gain that much life.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Plunge into Darkness

Choose one —
• Sacrifice any number of creatures. You gain 3 life for each creature sacrificed this way.
• Pay any amount of life, then look at that many cards from the top of your library. Put one of those cards into your hand and exile the rest.
Entwine {B} (Choose both if you pay the entwine cost.)

Withering Torment

Destroy target creature or enchantment. You lose 2 life.

Brash Taunter

Indestructible
Whenever this creature is dealt damage, it deals that much damage to target opponent.
{2}{R}, {T}: This creature fights another target creature.

Staff of the Flame Magus

Whenever you cast a red spell or a Mountain you control enters, you gain 1 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Terminate

Destroy target creature. It can't be regenerated.

Poet's Quill

When this Equipment enters, learn. (You may reveal a Lesson card you own from outside the game and put it into your hand, or discard a card to draw a card.)
Equipped creature gets +1/+1 and has lifelink.
Equip {1}{B}

Mask of Avacyn

Equipped creature gets +1/+2 and has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {3}

Baleful Ammit

Lifelink
When this creature enters, put a -1/-1 counter on target creature you control.

Canyon Slough

({T}: Add {B} or {R}.)
This land enters tapped.
Cycling {2} ({2}, Discard this card: Draw a card.)

Rakdos Carnarium

This land enters tapped.
When this land enters, return a land you control to its owner's hand.
{T}: Add {B}{R}.

Repercussion

Whenever a creature is dealt damage, this enchantment deals that much damage to that creature's controller.

Manabarbs

Whenever a player taps a land for mana, this enchantment deals 1 damage to that player.

Discerning Taste

Look at the top four cards of your library. Put one of them into your hand and the rest into your graveyard. You gain life equal to the greatest power among creature cards put into your graveyard this way.

Fists of the Demigod

Enchant creature
As long as enchanted creature is black, it gets +1/+1 and has wither. (It deals damage to creatures in the form of -1/-1 counters.)
As long as enchanted creature is red, it gets +1/+1 and has first strike.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature of their choice or pays 3 life.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Phyresis

Enchant creature
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Fate Unraveler

Whenever an opponent draws a card, this creature deals 1 damage to that player.

Bucknard's Everfull Purse

{1}, {T}: Roll a d4 and create a number of Treasure tokens equal to the result. The player to your right gains control of this artifact.

Thran Power Suit

Equipped creature gets +1/+1 for each Aura and Equipment attached to it and has ward {2}. (Whenever equipped creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Mountain

Blessing of Belzenlok

Target creature gets +2/+1 until end of turn. If it's legendary, it also gains lifelink until end of turn.

Fountain of Youth

Torbran, Thane of Red Fell

If a red source you control would deal damage to an opponent or a permanent an opponent controls, it deals that much damage plus 2 instead.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Ramosian Greatsword

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Equipped creature gets +3/+1 and has trample.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Luxa River Shrine

{1}, {T}: You gain 1 life. Put a brick counter on this artifact.
{T}: You gain 2 life. Activate only if there are three or more brick counters on this artifact.

Grab the Prize

As an additional cost to cast this spell, discard a card.
Draw two cards. If the discarded card wasn't a land card, Grab the Prize deals 2 damage to each opponent.

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Thrill of Possibility

As an additional cost to cast this spell, discard a card.
Draw two cards.

Leather Armor

Equipped creature gets +0/+1 and has ward {1}. (Whenever equipped creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {1}.)
Equip {0}. Activate only once each turn.

Jeweled Torque

As this artifact enters, choose a color.
Whenever a player casts a spell of the chosen color, you may pay {2}. If you do, you gain 2 life.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Citadel of Pain

At the beginning of each player's end step, this enchantment deals X damage to that player, where X is the number of untapped lands they control.

Sol Ring

Pristine Talisman

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Tenza, Godo's Maul

Equipped creature gets +1/+1. As long as it's legendary, it gets an additional +2/+2. As long as it's red, it has trample.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Deadly Wanderings

As long as you control exactly one creature, that creature gets +2/+0 and has deathtouch and lifelink.

Myriad Landscape

This land enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice this land: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Dictate of the Twin Gods

Flash
If a source would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Smoldering Marsh

({T}: Add {B} or {R}.)
This land enters tapped unless you control two or more basic lands.

Aether Flash

Whenever a creature enters, this enchantment deals 2 damage to it.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Burning Earth

Whenever a player taps a nonbasic land for mana, this enchantment deals 1 damage to that player.

Fanatic of Mogis

When this creature enters, it deals damage to each opponent equal to your devotion to red. (Each {R} in the mana costs of permanents you control counts toward your devotion to red.)

Desolation

At the beginning of each end step, each player who tapped a land for mana this turn sacrifices a land of their choice. This enchantment deals 2 damage to each player who sacrificed a Plains this way.

Temple of Malice

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {B} or {R}.

Fear of Lost Teeth

When this creature dies, it deals 1 damage to any target and you gain 1 life.

Diamond Pick-Axe

Indestructible (Effects that say "destroy" don't destroy this Equipment.)
Equipped creature gets +1/+1 and has "Whenever this creature attacks, create a Treasure token." (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")
Equip {2}

Mayhem Devil

Whenever a player sacrifices a permanent, this creature deals 1 damage to any target.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, this enchantment deals 1 damage to that player.

Mudbutton Torchrunner

When this creature dies, it deals 3 damage to any target.

Blood Moon

Persistent Constrictor

At the beginning of each opponent's upkeep, they lose 1 life and you put a -1/-1 counter on up to one target creature they control.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Shadowblood Ridge

Barbflare Gremlin

First strike, haste
Whenever a player taps a land for mana, if this creature is tapped, that player adds one mana of any type that land produced. Then that land deals 1 damage to that player.

Cackling Slasher

Deathtouch
This creature enters with a +1/+1 counter on it if a creature died this turn.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice this enchantment.
{B}: This enchantment deals 1 damage to each creature and each player.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Foreboding Ruins

As this land enters, you may reveal a Swamp or Mountain card from your hand. If you don't, this land enters tapped.
{T}: Add {B} or {R}.

Iridescent Vinelasher

Offspring {2} (You may pay an additional {2} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Landfall — Whenever a land you control enters, this creature deals 1 damage to target opponent.

Magus of the Moon

Dwarven Scorcher

Sacrifice this creature: This creature deals 1 damage to target creature unless that creature's controller has this creature deal 2 damage to them.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Fear of Burning Alive

When this creature enters, it deals 4 damage to each opponent.
Delirium — Whenever a source you control deals noncombat damage to an opponent, if there are four or more card types among cards in your graveyard, this creature deals that amount of damage to target creature that player controls.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Infernal Grasp

Destroy target creature. You lose 2 life.

Bedevil

Destroy target artifact, creature, or planeswalker.

Bloodfell Caves

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {B} or {R}.

Swamp

Rakdos Signet

Prism Ring

As this artifact enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Court of Ambition

When this enchantment enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Disciple of Griselbrand

{1}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Consuming Vapors

Target player sacrifices a creature of their choice. You gain life equal to that creature's toughness.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)