Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Mana Leak

Counter target spell unless its controller pays {3}.

Sinister Strength

Enchant creature
Enchanted creature gets +3/+1 and is black.

Island

Swamp

Plague Stinger

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Counterspell

Shadow Rift

Target creature gains shadow until end of turn. (It can block or be blocked by only creatures with shadow.)
Draw a card.

Spell Pierce

Counter target noncreature spell unless its controller pays {2}.

Ichorclaw Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Ichorclaw Myr becomes blocked, it gets +2/+2 until end of turn.

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Unstable Mutation

Enchant creature
Enchanted creature gets +3/+3.
At the beginning of the upkeep of enchanted creature's controller, put a -1/-1 counter on that creature.

Dark Favor

Enchant creature
When Dark Favor enters, you lose 1 life.
Enchanted creature gets +3/+1.