Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Counterspell

Sphinx of Foresight

You may reveal this card from your opening hand. If you do, scry 3 at the beginning of your first upkeep.
Flying
At the beginning of your upkeep, scry 1.

Ezio Auditore da Firenze

Menace
Assassin spells you cast have freerunning {B}{B}. (You may cast a spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Whenever Ezio deals combat damage to a player, you may pay {W}{U}{B}{R}{G} if that player has 10 or less life. When you do, that player loses the game.

Negate

Leyline of Abundance

If Leyline of Abundance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you tap a creature for mana, add an additional {G}.
{6}{G}{G}: Put a +1/+1 counter on each creature you control.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Elves of Deep Shadow

{T}: Add {B}. Elves of Deep Shadow deals 1 damage to you.

Eladamri's Call

Search your library for a creature card, reveal that card, put it into your hand, then shuffle.

Birthing Pod

({G/P} can be paid with either {G} or 2 life.)
{1}{G/P}, {T}, Sacrifice a creature: Search your library for a creature card with mana value equal to 1 plus the sacrificed creature's mana value, put that card onto the battlefield, then shuffle. Activate only as a sorcery.

Bello, Bard of the Brambles

During your turn, each non-Equipment artifact and non-Aura enchantment you control with mana value 4 or greater is a 4/4 Elemental creature in addition to its other types and has indestructible, haste, and "Whenever this creature deals combat damage to a player, draw a card."

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Chancellor of the Spires

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent mills seven cards.
Flying
When Chancellor of the Spires enters, you may cast target instant or sorcery card from an opponent's graveyard without paying its mana cost.

Neoform

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a creature card with mana value equal to 1 plus the sacrificed creature's mana value, put that card onto the battlefield with an additional +1/+1 counter on it, then shuffle.

Gemstone Caverns

If Gemstone Caverns is in your opening hand and you're not the starting player, you may begin the game with Gemstone Caverns on the battlefield with a luck counter on it. If you do, exile a card from your hand.
{T}: Add {C}. If Gemstone Caverns has a luck counter on it, instead add one mana of any color.

Leyline of Combustion

If Leyline of Combustion is in your opening hand, you may begin the game with it on the battlefield.
Whenever you and/or at least one permanent you control becomes the target of a spell or ability an opponent controls, Leyline of Combustion deals 2 damage to that player.

Leyline of Resonance

If Leyline of Resonance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you cast an instant or sorcery spell that targets only a single creature you control, copy that spell. You may choose new targets for the copy.

Leyline of the Guildpact

If Leyline of the Guildpact is in your opening hand, you may begin the game with it on the battlefield.
Each nonland permanent you control is all colors.
Lands you control are every basic land type in addition to their other types.

Scheming Symmetry

Choose two target players. Each of them searches their library for a card, then shuffles and puts that card on top.

Niv-Mizzet Reborn

Flying
When Niv-Mizzet Reborn enters, reveal the top ten cards of your library. For each color pair, choose a card that's exactly those colors from among them. Put the chosen cards into your hand and the rest on the bottom of your library in a random order.

Wishclaw Talisman

Wishclaw Talisman enters with three wish counters on it.
{1}, {T}, Remove a wish counter from Wishclaw Talisman: Search your library for a card, put it into your hand, then shuffle. An opponent gains control of Wishclaw Talisman. Activate only during your turn.

Perplex

Counter target spell unless its controller discards their hand.
Transmute {1}{U}{B} ({1}{U}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Eldritch Evolution

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a creature card with mana value X or less, where X is 2 plus the sacrificed creature's mana value. Put that card onto the battlefield, then shuffle. Exile Eldritch Evolution.

Simian Spirit Guide

Exile Simian Spirit Guide from your hand: Add {R}.

Leyline of Lightning

If Leyline of Lightning is in your opening hand, you may begin the game with it on the battlefield.
Whenever you cast a spell, you may pay {1}. If you do, Leyline of Lightning deals 1 damage to target player or planeswalker.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Worldly Tutor

Search your library for a creature card, reveal it, then shuffle and put the card on top.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Leyline of the Meek

If Leyline of the Meek is in your opening hand, you may begin the game with it on the battlefield.
Creature tokens get +1/+1.

Diabolic Intent

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card, put that card into your hand, then shuffle.

Chancellor of the Forge

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, create a 1/1 red Phyrexian Goblin creature token with haste.
When Chancellor of the Forge enters, create X 1/1 red Phyrexian Goblin creature tokens with haste, where X is the number of creatures you control.

Sylvan Tutor

Search your library for a creature card, reveal it, then shuffle and put that card on top.

Prime Speaker Vannifar

{T}, Sacrifice another creature: Search your library for a creature card with mana value equal to 1 plus the sacrificed creature's mana value, put that card onto the battlefield, then shuffle. Activate only as a sorcery.

Imperial Seal

Leyline of Lifeforce

If Leyline of Lifeforce is in your opening hand, you may begin the game with it on the battlefield.
Creature spells can't be countered.

Chancellor of the Annex

You may reveal this card from your opening hand. If you do, when each opponent casts their first spell of the game, counter that spell unless that player pays {1}.
Flying
Whenever an opponent casts a spell, counter it unless that player pays {1}.

Leyline Axe

If this card is in your opening hand, you may begin the game with it on the battlefield.
Equipped creature gets +1/+1 and has double strike and trample.
Equip {3} ({3}: Attach to target creature you control. Equip only as a sorcery.)

Leyline of Mutation

If Leyline of Mutation is in your opening hand, you may begin the game with it on the battlefield.
You may pay {W}{U}{B}{R}{G} rather than pay the mana cost for spells you cast.

Leyline of Vitality

If Leyline of Vitality is in your opening hand, you may begin the game with it on the battlefield.
Creatures you control get +0/+1.
Whenever a creature you control enters, you may gain 1 life.

Fanatic of Rhonas

{T}: Add {G}.
Ferocious — {T}: Add {G}{G}{G}{G}. Activate only if you control a creature with power 4 or greater.
Eternalize {2}{G}{G} ({2}{G}{G}, Exile this card from your graveyard: Create a token that's a copy of it, except it's a 4/4 black Zombie Snake Druid with no mana cost. Eternalize only as a sorcery.)

Serum Powder

{T}: Add {C}.
Any time you could mulligan and Serum Powder is in your hand, you may exile all the cards from your hand, then draw that many cards. (You can do this in addition to taking mulligans.)

Selective Memory

Search your library for any number of nonland cards, exile them, then shuffle.

Elvish Spirit Guide

Exile Elvish Spirit Guide from your hand: Add {G}.

Leyline of Singularity

If Leyline of Singularity is in your opening hand, you may begin the game with it on the battlefield.
All nonland permanents are legendary.

Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Leyline of Hope

If Leyline of Hope is in your opening hand, you may begin the game with it on the battlefield.
If you would gain life, you gain that much life plus 1 instead.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Leyline of Transformation

If Leyline of Transformation is in your opening hand, you may begin the game with it on the battlefield.
As Leyline of Transformation enters, choose a creature type.
Creatures you control are the chosen type in addition to their other types. The same is true for creature spells you control and creature cards you own that aren't on the battlefield.

Devourer of Destiny

You may reveal this card from your opening hand. If you do, at the beginning of your first upkeep, look at the top four cards of your library. You may put one of those cards back on top of your library. Exile the rest.
When you cast this spell, exile target permanent that's one or more colors.

Green Sun's Zenith

Search your library for a green creature card with mana value X or less, put it onto the battlefield, then shuffle. Shuffle Green Sun's Zenith into its owner's library.

Leyline of Anticipation

If Leyline of Anticipation is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.

Chancellor of the Tangle

You may reveal this card from your opening hand. If you do, at the beginning of your first main phase of the game, add {G}.
Vigilance, reach

Leyline of Punishment

If Leyline of Punishment is in your opening hand, you may begin the game with it on the battlefield.
Players can't gain life.
Damage can't be prevented.