Hand of Vecna

At the beginning of combat on your turn, equipped creature or a creature you control named Vecna gets +X/+X until end of turn, where X is the number of cards in your hand.
Equip—Pay 1 life for each card in your hand.
Equip {2}

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Rottenmouth Viper

As an additional cost to cast this spell, you may sacrifice any number of nonland permanents. This spell costs {1} less to cast for each permanent sacrificed this way.
Whenever Rottenmouth Viper enters or attacks, put a blight counter on it. Then for each blight counter on it, each opponent loses 4 life unless that player sacrifices a nonland permanent of their choice or discards a card.

The Book of Vile Darkness

At the beginning of your end step, if you lost 2 or more life this turn, create a 2/2 black Zombie creature token.
{T}, Exile The Book of Vile Darkness and artifacts you control named Eye of Vecna and Hand of Vecna: Create Vecna, a legendary 8/8 black Zombie God creature token with indestructible and all triggered abilities of the exiled cards.

Wand of Orcus

Whenever equipped creature attacks or blocks, it and Zombies you control gain deathtouch until end of turn.
Whenever equipped creature deals combat damage to a player, create that many 2/2 black Zombie creature tokens.
Equip {3}

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Cryptbreaker

{1}{B}, {T}, Discard a card: Create a 2/2 black Zombie creature token.
Tap three untapped Zombies you control: You draw a card and you lose 1 life.

Maha, Its Feathers Night

Flying, trample
Ward—Discard a card.
Creatures your opponents control have base toughness 1.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Containment Construct

Whenever you discard a card, you may exile that card from your graveyard. If you do, you may play that card this turn.

Abolisher of Bloodlines

Flying
When this creature transforms into Abolisher of Bloodlines, target opponent sacrifices three creatures of their choice.

Voldaren Pariah

Flying
Sacrifice three other creatures: Transform Voldaren Pariah.
Madness {B}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Voldaren Pariah // Abolisher of Bloodlines

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Scampering Surveyor

When Scampering Surveyor enters, search your library for a basic land card or Cave card, put it onto the battlefield tapped, then shuffle.

Swamp

Larceny

Whenever a creature you control deals combat damage to a player, that player discards a card.

Fell

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Demonic Embrace

Enchant creature
Enchanted creature gets +3/+1, has flying, and is a Demon in addition to its other types.
You may cast Demonic Embrace from your graveyard by paying 3 life and discarding a card in addition to paying its other costs.

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Gisa's Bidding

Create two 2/2 black Zombie creature tokens.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Dark Ritual

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Fell Mire

As Fell Mire enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {B}.

Fell the Profane

Fell the Profane // Fell Mire

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Doomsday Confluence

Choose X. You may choose the same mode more than once.
• Each player sacrifices a nonartifact creature of their choice.
• Create a 3/3 black Dalek artifact creature token with menace.
• Each opponent discards a card.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Dying to Serve

Whenever you discard one or more cards, create a tapped 2/2 black Zombie creature token. This ability triggers only once each turn.

Needle Specter

Flying
Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever Needle Specter deals combat damage to a player, that player discards that many cards.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

From Under the Floorboards

Madness {X}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)
Create three tapped 2/2 black Zombie creature tokens and you gain 3 life. If this spell's madness cost was paid, instead create X of those tokens and you gain X life.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Abyssal Nocturnus

Whenever an opponent discards a card, Abyssal Nocturnus gets +2/+2 and gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Endless Atlas

{2}, {T}: Draw a card. Activate only if you control three or more lands with the same name.

Capital Punishment

Council's dilemma — Starting with you, each player votes for death or taxes. Each opponent sacrifices a creature of their choice for each death vote and discards a card for each taxes vote.

Archon of Cruelty

Flying
Whenever Archon of Cruelty enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Feast of Sanity

Whenever you discard a card, Feast of Sanity deals 1 damage to any target and you gain 1 life.

Honden of Night's Reach

At the beginning of your upkeep, target opponent discards a card for each Shrine you control.

Sol Ring

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Tinybones Joins Up

When Tinybones Joins Up enters, any number of target players each discard a card.
Whenever a legendary creature you control enters, any number of target players each mill a card and lose 1 life.

Night's Whisper

Bone Miser

Whenever you discard a creature card, create a 2/2 black Zombie creature token.
Whenever you discard a land card, add {B}{B}.
Whenever you discard a noncreature, nonland card, draw a card.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Barbed Servitor

Indestructible
When Barbed Servitor enters, suspect it. (It has menace and can't block.)
Whenever Barbed Servitor deals combat damage to a player, you draw a card and you lose 1 life.
Whenever Barbed Servitor is dealt damage, target opponent loses that much life.

Reliquary Tower

The Core

(Transforms from Matzalantli.)
Fathomless descent — {T}: Add X mana of any one color, where X is the number of permanent cards in your graveyard.

Matzalantli, the Great Door

{T}: Draw a card, then discard a card.
{4}, {T}: Transform Matzalantli, the Great Door. Activate only if there are four or more permanent types among cards in your graveyard. (Artifact, battle, creature, enchantment, land, and planeswalker are permanent types.)

Matzalantli, the Great Door // The Core

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.

Bloodthorn Flail

Equipped creature gets +2/+1.
Equip—Pay {3} or discard a card.

Archfiend of Ifnir

Flying
Whenever you cycle or discard another card, put a -1/-1 counter on each creature your opponents control.
Cycling {2} ({2}, Discard this card: Draw a card.)

Sign in Blood

Target player draws two cards and loses 2 life.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Tinybones, Bauble Burglar

Whenever an opponent discards a card, exile it from their graveyard with a stash counter on it.
During your turn, you may play cards you don't own with stash counters on them from exile, and mana of any type can be spent to cast those spells.
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Strength of Lunacy

Enchant creature
Enchanted creature gets +2/+1 and has protection from white.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Pip-Boy 3000

Whenever equipped creature attacks, choose one —
• Sort Inventory — Draw a card, then discard a card.
• Pick a Perk — Put a +1/+1 counter on that creature.
• Check Map — Untap up to two target lands.
Equip {2}